CAS Number15191-21-6
Synonyms(S)-2-Formamido-3-(1H-imidazol-4-yl)propanoic acid; N-Formyl-L-histidine; N-formyl histidine; Einecs 239-248-1; Formylhistidine
Molecular FormulaC7H9O3N3
Molecular Weight183.17
Density1.51g/cm3
Boiling Point442.9ºC at 760mmHg
Melting Point202.0 to 206.0 °C
AppearanceSolid;White to Almost white powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 15191-21-6 |
| Catalog No. | 2A-9082567 |
| Chinese Name | N-甲酰基-L-组氨酸 |
| Synonyms | (S)-2-Formamido-3-(1H-imidazol-4-yl)propanoic acid; N-Formyl-L-histidine; N-formyl histidine; Einecs 239-248-1; Formylhistidine |
| Molecular Formula | C7H9O3N3 |
| Molecular Weight | 183.17 |
| Density | 1.51g/cm3 |
| Boiling Point | 442.9ºC at 760mmHg |
| Melting Point | 202.0 to 206.0 °C |
| Appearance | Solid;White to Almost white powder to crystal |
| Water Solubility | almost transparency |
| Application | N-formyl-L-istidine has binding affinity with histidine tRNA synthetase, with a Ki value of 4.6 μM. N-formyl-L-histidine has a competitive inhibitory effect on L-histidine ammonia lyase, inhibiting th |
| HTC | 2933290090 |
| MDL Number | MFCD00059159 |
| SMILES | O=CNC(Cc1cnc[nH]1)C(=O)O |
| InChI | InChI=1S/C7H9N3O3/c11-4-10-6(7(12)13)1-5-2-8-3-9-5/h2-4,6H,1H2,(H,8,9)(H,10,11)(H,12,13) |
| InChI Key | WFQVSLVQIFFQQN-LURJTMIESA-N |
| MSDS | msds/82567_1_15191_21_6.pdf |
| Bioactivity | N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Lepore GC, et al. Histidyl-tRNA synthetase from Salmonella typhimurium: specificity in the binding of histidine analogues. Eur J Biochem. 1975 Aug 15;56(2):369-74. [2]. Shibatani T, et al. Crystalline L-histidine ammonia-lyase of Achromobacter liquidum. Crystallization and enzymic properties. Eur J Biochem. 1975 Jun 16;55(1):263-9. Chemical & Physical Properties Density 1.51g/cm3 Boiling Point 442.9ºC at 760mmHg Melting Point 202.0 to 206.0 °C Molecular Formula C7H9N3O3 Molecular Weight 183.16500 Flash Point 221.6ºC Exact Mass 183.06400 PSA 95.08000 LogP 0.17820 Vapour Pressure 1.72E-17mmHg at 25°C Index of Refraction 58 ° (C=2, H2O) InChIKey WFQVSLVQIFFQQN-LURJTMIESA-N SMILES O=CNC(Cc1cnc[nH]1)C(=O)O Water Solubility almost transparency |
| Use of | Properties Name n-formyl-l-histidine Synonym More Synonyms L-Histidine, N-formyl Biological Activity Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Lepore GC, et al. Histidyl-tRNA synthetase from Salmonella typhimurium: specificity in the binding of histidine analogues. Eur J Biochem. 1975 Aug 15;56(2):369-74. [2]. Shibatani T, et al. Crystalline L-histidine ammonia-lyase of Achromobacter liquidum. Crystallization and enzymic properties. Eur J Biochem. 1975 Jun 16;55(1):263-9. Chemical & Physical Properties Molecular Formula C7H9N3O3 Exact Mass 183.06400 PSA 95.08000 LogP 0.17820 InChIKey WFQVSLVQIFFQQN-LURJTMIESA-N Water Solubility almost transparency |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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