
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 33390-41-9 |
| Catalog No. | 2A-9069011 |
| Chinese Name | 8-Deoxygartanin |
| Synonyms | 8-Deoxygartanin; 1,3,5-Trihydroxy-2,4-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one |
| Molecular Formula | C23H24O5 |
| Molecular Weight | 380.44 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 595.7±50.0 °C at 760 mmHg |
| Appearance | yellow powder |
| Storage Condition | 2-8℃, dry, sealed |
| Application | 8-Deoxygartanin is a prenylated xanthones found in mangosteen. 8-Deoxygartanin is a selective inhibitor of butylcholinesterase (BChE). 8-Deoxygartanin has anti-Plasmodium activity with an IC50 value o |
| HTC | 2932999099 |
| MDL Number | C23H24O5 |
| MSDS | msds/69011_1_33390_41_9.pdf |
| Use of | 8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3]. Properties Name 8-desoxygartanin Synonym More Synonyms 8-Deoxygartanin Biological Activity Description 8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3]. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection p65:11.3 μM (IC50) References [1]. Khaw KY, et al. Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies. Phytomedicine. 2014 Sep 25;21(11):1303-9. [2]. Ngouamegne ET, et al. Endodesmiadiol, a friedelane triterpenoid, and other antiplasmodial compounds from Endodesmia calophylloides. Chem Pharm Bull (Tokyo). 2008 Mar;56(3):374-7. [3]. Han AR, et al. Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). J Nat Prod. 2009 Nov;72(11):2028-31. Chemical & Physical Properties Molecular Formula C23H24O5 Exact Mass 380.162384 PSA 90.90000 Index of Refraction 1.637 Safety Information Hazard Codes Xi HS Code 2932999099 Synthetic Route 2,3-Dimethoxybe... CAS#:1521-38-6 8-Deoxygartanin CAS#:33390-41-9 Literature: Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300 2,3-DIMETHOXYBE... CAS#:7169-06-4 8-Deoxygartanin CAS#:33390-41-9 Literature: Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300 1,3,5-trimethox... CAS#:6563-50-4 8-Deoxygartanin CAS#:33390-41-9 Literature: Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300 Precursor & DownStream Precursor 4 CAS#:1521-38-6 2,3-Dimethoxybe... CAS#:7169-06-4 2,3-DIMETHOXYBE... CAS#:6563-50-4 1,3,5-trimethox... CAS#:6343-00-6 (2-hydroxy-3-me... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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