
CAS Number22112-89-6
Synonyms5,15-Diphenyl-21H,23H-porphine,5,15-Diphenylporphyrin,5,15-diphenyl-Porphine; 21H,23H-5,15-diphenylporphine; 5,15-Diphenylporphyrin; 10,20-diphenylporphyrin; 10,20-diphenylporphyrine; 5,15-diphenyl-21H,23H-porphyrin; 5,15-Diphenyl-21H,23H-porphine; 5,15-diphenylphorphyrin; 21H,23H-Porphine,5,15-diphenyl; 5,15-diphenylporphine
Molecular FormulaC32H22N4
Molecular Weight462.54
Density1.3±0.1 g/cm3
Boiling Point912.3±65.0 °C at 760 mmHg
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 22112-89-6 |
| Catalog No. | 2A-9068402 |
| Chinese Name | 5,15-二苯基卟啉 |
| Synonyms | 5,15-Diphenyl-21H,23H-porphine,5,15-Diphenylporphyrin,5,15-diphenyl-Porphine; 21H,23H-5,15-diphenylporphine; 5,15-Diphenylporphyrin; 10,20-diphenylporphyrin; 10,20-diphenylporphyrine; 5,15-diphenyl-21H,23H-porphyrin; 5,15-Diphenyl-21H,23H-porphine; 5,15-diphenylphorphyrin; 21H,23H-Porphine,5,15-diphenyl; 5,15-diphenylporphine |
| Molecular Formula | C32H22N4 |
| Molecular Weight | 462.54 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 912.3±65.0 °C at 760 mmHg |
| Appearance | powder |
| Application | 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50 for STAT3 and STAT1 are 0.28µM and 10µM, respectively) [1]. |
| HTC | 2933990090 |
| PubChem ID | 329798793 |
| MDL Number | MFCD08276335 |
| SMILES | c1ccc(cc1)-c2c3ccc(cc4ccc([nH]4)c(-c5ccccc5)c6ccc(cc7ccc2[nH]7)n6)n3 |
| InChI | 1S/C32H22N4/c1-3-7-21(8-4-1)31-27-15-11-23(33-27)19-25-13-17-29(35-25)32(22-9-5-2-6-10-22)30-18-14-26(36-30)20-24-12-16-28(31)34-24/h1-20,33,36H/b23-19-,24-20-,25-19-,26-20-,31-27-,31-28-,32-29-,32-30- |
| InChI Key | FNNOEKVUXXVPAI-DUVOQLPESA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/68402_1_22112_89_6.pdf |
| Bioactivity | 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50s of 0.28 µM and 10 µM for STAT3 and STAT1, respectively)[1]. Related Catalog Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT References [1]. Uehara Y, et al. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009;380(3):627-631. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 912.3±65.0 °C at 760 mmHg Molecular Formula C32H22N4 Molecular Weight 462.544 Flash Point 401.3±27.2 °C Exact Mass 462.184448 PSA 56.30000 LogP 8.49 Vapour Pressure 0.0±0.3 mmHg at 25°C Index of Refraction 1.705 InChIKey QIBKIAFNCVIIMG-UHFFFAOYSA-N SMILES C1=Cc2nc1cc1nc(c(-c3ccccc3)c3ccc(cc4ccc([nH]4)c2-c2ccccc2)[nH]3)C=C1 |
| Use of | 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50s of 0.28 µM and 10 µM for STAT3 and STAT1, respectively)[1]. Properties Name 10,20-diphenyl-21,22-dihydroporphyrin Synonym More Synonyms 5,15-DIPHENYL-21H,23H-PORPHINE Biological Activity Description 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50s of 0.28 µM and 10 µM for STAT3 and STAT1, respectively)[1]. Related Catalog Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT References [1]. Uehara Y, et al. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009;380(3):627-631. Chemical & Physical Properties Molecular Formula C32H22N4 Exact Mass 462.184448 PSA 56.30000 Index of Refraction 1.705 InChIKey QIBKIAFNCVIIMG-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 90.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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