CAS Number61-33-6
Synonymscilloral; MFCD00036193; benzyl penicillin; cosmopen; dropcillin; cilopen; abbocillin; galofak; Penicillin II; Pencillin G; pradupen; Ursopen; penicillin G; gelacillin; EINECS 204-038-0; pencilling
Molecular FormulaC16H18N2O4S
Molecular Weight372.48
Purity95.0 - 102.0%
Density1.4±0.1 g/cm3
Boiling Point663.3±55.0 °C at 760 mmHg
Appearancepowder
EINECS204-038-0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 61-33-6 |
| Catalog No. | 2A-9000067 |
| Chinese Name | 青霉素 |
| Synonyms | cilloral; MFCD00036193; benzyl penicillin; cosmopen; dropcillin; cilopen; abbocillin; galofak; Penicillin II; Pencillin G; pradupen; Ursopen; penicillin G; gelacillin; EINECS 204-038-0; pencilling |
| Molecular Formula | C16H18N2O4S |
| Molecular Weight | 372.48 |
| Purity | 95.0 - 102.0 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 663.3±55.0 °C at 760 mmHg |
| Appearance | powder |
| Water Solubility | H2O: 100 mg/mL |
| Storage Condition | Ventilated low-temperature drying |
| Application | Penicillin G is a potent penicillin inhibitor. Penicillin G can be used for bacterial infections [1]. |
| EINECS | 204-038-0 |
| HTC | 32041900 |
| PubChem ID | 57654576 |
| MDL Number | MFCD00036193 |
| SMILES | [K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O |
| InChI | 1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1 |
| InChI Key | IYNDLOXRXUOGIU-LQDWTQKMSA-M |
| Beilstein/REAXYS | 3832841 |
| NACRES Code | NA.85 |
| UNSPSC | 51283424 |
| MSDS | msds/67_1_61_33_6.pdf |
| Use of | Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection[1]. Properties Name benzylpenicillin Synonym More Synonyms Penicillin-G Biological Activity Description Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection[1]. Related Catalog Research Areas >> Infection References [1]. Li D, et al. Determination of penicillin G and its degradation products in a penicillin production wastewater treatment plant and the receiving river. Water Res. 2008 Jan;42(1-2):307-17. Chemical & Physical Properties Molecular Formula C16H18N2O4S Exact Mass 334.098724 PSA 112.01000 Appearance of Characters powder Index of Refraction 1.655 InChIKey JGSARLDLIJGVTE-MBNYWOFBSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenylacetamido)- CAS REGISTRY NUMBER : BEILSTEIN REFERENCE NO. : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C16-H18-N2-O4-S MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T45 ANV ESTJ CMV1R& F F GVQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Human - child DOSE/DURATION : 15000 units/kg TOXIC EFFECTS : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5700 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1118 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 4940 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : TOXIC EFFECTS : Brain and Coverings - other degenerative changes TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 104 ku/kg/4D-I TOXIC EFFECTS : Blood - changes in other cell count (unspecified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 750 units/kg/5D-I TOXIC EFFECTS : Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Immunological Including Allergic - decrease in humoral immune response Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Microorganism - not otherwise specified DOSE/DURATION : REFERENCE : Safety Information Hazard Codes Xn WGK Germany 2 RTECS XH9700000 HS Code 32041900 Synthetic Route 6-Aminopenicill... Penicillin-G Literature: Konig; Hans-Bodo; Schrock; Wilfried; Bayer Aktiengesellschaft Patent: US3933795 A1, 1976 ; ampicillin Trih... Penicillin-G Literature: US4031229 A1, ; 6-Aminopenicill... Phenylacetyl ch... Penicillin-G Literature: Journal of the American Chemical Society, , vol. 81, p. 5838 Journal of the American Chemical Society, , vol. 84, p. 2893,2987 Nature (London, United Kingdom), , vol. 183, p. 257 Precursor & DownStream Precursor 9 CAS#:551-16-6 6-Aminopenicill... CAS#:5187-94-0 ampicillin Trih... CAS#:103-80-0 Phenylacetyl ch... CAS#:1254-56-4 benzyl 6β-pheny... DownStream 8 CAS#:551-16-6 6-Aminopenicill... CAS#:103-82-2 Phenylacetic acid CAS#:52-67-5 D-penicillamine CAS#:13057-98-2 2-Thiazolidinea... |
| Transport Info | Product Name: Penicillin G |
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