CAS Number2921-57-5
SynonymsUrbason-Soluble; methylprednisolone 21-hemisuccinate; Butanedioic acid, mono[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester; MFCD00271782; 4-{[(6α,11β)-11,17-Dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoic acid; Methylprednisolone sodium hemisuccinate; 6-methylprednisolone-21-hemisuccinate; methylprednisolone hemisuccinate esters; Methylprednisolone hydrogen succinate; Solumedrol; EINECS 220-863-9; UNII-5GMR90S4KN; METHYLPREDNISOLONE SODIUM SUCCINATE; 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-(Hydrogen Succinate); Methylprednisolone hemisuccinate; methylprednisolone succinate
Molecular FormulaC26H34O8
Molecular Weight474.543
Purity99%
Density1.3±0.1 g/cm3
Boiling Point689.6±55.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2921-57-5 |
| Catalog No. | 2A-9006682 |
| Chinese Name | 甲基泼尼松龙琥珀酸酯 |
| Synonyms | Urbason-Soluble; methylprednisolone 21-hemisuccinate; Butanedioic acid, mono[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester; MFCD00271782; 4-{[(6α,11β)-11,17-Dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoic acid; Methylprednisolone sodium hemisuccinate; 6-methylprednisolone-21-hemisuccinate; methylprednisolone hemisuccinate esters; Methylprednisolone hydrogen succinate; Solumedrol; EINECS 220-863-9; UNII-5GMR90S4KN; METHYLPREDNISOLONE SODIUM SUCCINATE; 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-(Hydrogen Succinate); Methylprednisolone hemisuccinate; methylprednisolone succinate |
| Molecular Formula | C26H34O8 |
| Molecular Weight | 474.543 |
| Purity | 99 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 689.6±55.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | Methylprednisolone succinate is a synthetic glucocorticoid that is widely used as an anti-inflammatory agent. |
| HTC | 2942000000 |
| SMILES | CC1CC2C(C(O)CC3(C)C2CCC3(O)C(=O)COC(=O)CCC(=O)O)C2(C)C=CC(=O)C=C12 |
| InChI | InChI=1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1 |
| InChI Key | IMBXEJJVJRTNOW-XYMSELFBSA-N |
| Use of | Methylprednisolone succinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent. Properties Articles25 Name 4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid Synonym More Synonyms Methylprednisolone succinate Biological Activity Description Methylprednisolone succinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent. Related Catalog Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor Research Areas >> Cancer Research Areas >> Inflammation/Immunology glucocorticoid receptor[1] References [1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6. [2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000. Chemical & Physical Properties Molecular Formula C26H34O8 Exact Mass 474.225372 PSA 138.20000 Index of Refraction 1.593 InChIKey IMBXEJJVJRTNOW-XYMSELFBSA-N Storage condition 2-8℃ Safety Information RIDADR NONH for all modes of transport HS Code 2942000000 Synthetic Route Total: 1 Page methylprednisol... CAS#:77074-42-1 Methylprednisolone CAS#:83-43-2 Methylprednisol... CAS#:2921-57-5 Literature: Anderson; Conradi; Lambert Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 5 p. 604 - 610 methylprednisol... CAS#:77074-42-1 Methylprednisol... CAS#:2921-57-5 Literature: Anderson; Taphouse Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 2 p. 181 - 186 |
| Transport Info | Product name: Methylprednisolone succinate |
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