CAS Number520-12-7
Synonyms4'-Methylcapillarisin; 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 6-Hydroxypelargidenon-6,4'-dimethyl Ether; 6-Methoxyacacetin; 5,7-dihydroxy-6,4'-dimethoxyflavone; 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)chromen-4-one; pictolinarigenin; scutellarein-6,4'-dimethyl ether; Pectolinarigenin; Pectolinaringenin; 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-4',6-dimethoxyflavone
Molecular FormulaC17H14O6
Molecular Weight314.29
Purity≥98.0 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point565.5±50.0 °C at 760 mmHg
Melting Point220-223°
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 520-12-7 |
| Catalog No. | 2A-9066469 |
| Chinese Name | 柳穿鱼黄素 |
| Synonyms | 4'-Methylcapillarisin; 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 6-Hydroxypelargidenon-6,4'-dimethyl Ether; 6-Methoxyacacetin; 5,7-dihydroxy-6,4'-dimethoxyflavone; 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)chromen-4-one; pictolinarigenin; scutellarein-6,4'-dimethyl ether; Pectolinarigenin; Pectolinaringenin; 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-4',6-dimethoxyflavone |
| Molecular Formula | C17H14O6 |
| Molecular Weight | 314.29 |
| Purity | ≥98.0 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 565.5±50.0 °C at 760 mmHg |
| Melting Point | 220-223° |
| Storage Condition | 2-8C |
| Application | Pectolinarigenin, isolated from Cirsium chanroenicum, is a dual inhibitor of COX-2/5-LOX. Has anti-inflammatory activity. Pectolinarigenin has a potent inhibitory effect on melanogenesis. |
| HTC | 2914509090 |
| MDL Number | MFCD00017444 |
| SMILES | [o]1c2c([c](cc1c3ccc(cc3)OC)=O)c(c(c(c2)O)OC)O |
| InChI | 1S/C17H14O6/c1-21-10-5-3-9(4-6-10)13-7-11(18)15-14(23-13)8-12(19)17(22-2)16(15)20/h3-8,19-20H,1-2H3 |
| InChI Key | GPQLHGCIAUEJQK-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/66469_1_520_12_7.pdf |
| Use of | Properties Name pectolinarigenin Synonym More Synonyms Pectolinarigenin Biological Activity Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase References [1]. Lim H, et al. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull. 2008 Nov;31(11):2063-7. [2]. Lee S, et al. Pectolinarigenin, an aglycone of pectolinarin, has more potent inhibitory activities on melanogenesis than pectolinarin.Biochem Biophys Res Commun. 2017 Nov 4;493(1):765-772. Chemical & Physical Properties Molecular Formula C17H14O6 Exact Mass 314.079041 PSA 89.13000 Index of Refraction 1.646 Safety Information HS Code 2914509090 Synthetic Route Pectolinarin CAS#:28978-02-1 Pectolinarigenin CAS#:520-12-7 Literature: Bonesi, Marco; Tundis, Rosa; Deguin, Brigitte; Loizzo, Monica R.; Menichini, Federica; Tillequin, Francois; Menichini, Francesco Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5431 - 5434 4',5,6-trimetho... CAS#:77733-15-4 Pectolinarigenin CAS#:520-12-7 Literature: Dong a Pharmaceutical Co., Ltd. Patent: US6025387 A1, 2000 ; 1-(2,4-dihydrox... CAS#:7499-99-2 Benzoic acid,4-... CAS#:794-94-5 Pectolinarigenin CAS#:520-12-7 Literature: Wessely; Kallab Monatshefte fuer Chemie, 1932 , vol. 60, p. 26,30 Full Text Show Details Wessely; Moser Monatshefte fuer Chemie, 1930 , vol. 56, p. 97,101, 104 Precursor & DownStream Precursor 7 CAS#:28978-02-1 Pectolinarin CAS#:77733-15-4 4',5,6-trimetho... CAS#:7499-99-2 1-(2,4-dihydrox... CAS#:794-94-5 Benzoic acid,4-... DownStream 0 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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