CAS Number155206-00-1
SynonymsBiMapnost; Prostamide; 17-Phenyl-tri-norprostaglandin F2α-ethyl amide; MFCD03411999; Lumigan
Molecular FormulaC25H37NO4
Molecular Weight415.57
Purity99%
Density1.1±0.1 g/cm3
Boiling Point629.8±55.0 °C at 760 mmHg
Melting Point66-68°C
Appearancecrystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 155206-00-1 |
| Catalog No. | 2A-9060157 |
| Chinese Name | 比马前列素 |
| Synonyms | BiMapnost; Prostamide; 17-Phenyl-tri-norprostaglandin F2α-ethyl amide; MFCD03411999; Lumigan |
| Molecular Formula | C25H37NO4 |
| Molecular Weight | 415.57 |
| Purity | 99 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 629.8±55.0 °C at 760 mmHg |
| Melting Point | 66-68°C |
| Appearance | crystalline solid |
| Storage Condition | −20°C |
| Application | Bimatoprost is a prostaglandin analog that acts on intraocular hypertension and glaucoma. |
| MDL Number | MFCD03411999 |
| SMILES | N(CC)C(=O)CCC\C=C/C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)\C=C\[C@@H](O)CCc2ccccc2 |
| InChI | InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1 |
| InChI Key | AQOKCDNYWBIDND-FTOWTWDKSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 12352211 |
| Hazard Symbols | transportation |
| MSDS | msds/60157_1_155206_00_1.pdf |
| Bioactivity | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.Target: Prostaglandin ReceptorBimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse. In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue.Bimatoprost activates prostamide alpha F2 receptors found in the hair follicle to stimulate its growth rate. Research led by Professor Randall and the University of Bradford found that it may also offer a treatment for scalp hair regrowth in trials conducted on samples taken from men undergoing hair transplants. According to Allergan's package labeling, users of its Latisse cosmetic product didn't develop darker irises in clinical studies; however, "patients should be advised about the potential for increased brown iris pigmentation which is likely to be permanent." Related Catalog Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Others References [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7. [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 629.8±55.0 °C at 760 mmHg Melting Point 66-68°C Molecular Formula C25H37NO4 Molecular Weight 415.566 Flash Point 334.7±31.5 °C Exact Mass 415.272247 PSA 89.79000 LogP 1.98 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.591 InChIKey AQOKCDNYWBIDND-UDIRQSBCSA-N SMILES CCNC(=O)CCCC=CCC1C(O)CC(O)C1C=CC(O)CCc1ccccc1 Storage condition −20°C |
| Use of | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.Target: Prostaglandin ReceptorBimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse. In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue.Bimatoprost activates prostamide alpha F2 receptors found in the hair follicle to stimulate its growth rate. Research led by Professor Randall and the University of Bradford found that it may also offer a treatment for scalp hair regrowth in trials conducted on samples taken from men undergoing hair transplants. According to Allergan's package labeling, users of its Latisse cosmetic product didn't develop darker irises in clinical studies; however, "patients should be advised about the potential for increased brown iris pigmentation which is likely to be permanent." Properties Articles28 Name bimatoprost Synonym More Synonyms Bimatoprost Biological Activity Description Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.Target: Prostaglandin ReceptorBimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse. In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue.Bimatoprost activates prostamide alpha F2 receptors found in the hair follicle to stimulate its growth rate. Research led by Professor Randall and the University of Bradford found that it may also offer a treatment for scalp hair regrowth in trials conducted on samples taken from men undergoing hair transplants. According to Allergan's package labeling, users of its Latisse cosmetic product didn't develop darker irises in clinical studies; however, "patients should be advised about the potential for increased brown iris pigmentation which is likely to be permanent." Related Catalog Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Others References [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7. [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7. Chemical & Physical Properties Molecular Formula C25H37NO4 Exact Mass 415.272247 PSA 89.79000 Index of Refraction 1.591 InChIKey AQOKCDNYWBIDND-UDIRQSBCSA-N |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Acrylimidamide | 19408-49-2 | 2A-9060148 |
| (Z)-3-aminoacrylamide | 74043-27-9 | 2A-9060149 |
| 2-CHLORO-6-NITROBENZYLAMINE | 2A-351689 | 2A-9060151 |
| 4-ETHYNYL-BENZOIC ACID METHYL ESTER | 3034-86-4 | 2A-9060153 |
| LAURYL DIMETHYLAMINE OXIDE | 70592-80-2 | 2A-9060155 |
| ANTIMONY DICHLOROTRIFLUORIDE | 7791-16-4 | 2A-9060158 |
| ETHYL 2-CYANOACRYLATE | 7085-85-0 | 2A-9060159 |
| trifluoroethane | 27987-06-0 | 2A-9060160 |
| ETHYL 4-HYDROXYMANDELATE | 68758-68-9 | 2A-9060162 |
| BILASTINE | 202189-78-4 | 2A-9060164 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS