CAS Number1132-68-9
SynonymsL-4-FLUOROPHE; (2R)-2-Amino-3-(4-fluorophenyl)propanoic acid; D,L-p-fluorophenylalanine; L-4-F-Phe-OH; L-p-fluorophenylalanine; 4-Fluorophenylalanine; H-Phe(4-F)-OH; H-L-PHE(4-F)-OH; L-4-Fluorophenylalanine; 4-fluoroPhe; RARECHEM BK PT 0031; (2R)-2-amino-3-(4-fluorophenyl)propionic acid; D-4-Fluorophenylalanine; para-fluoro-l-phenylalanine; H-PHE(P-F)-OH; D-4-Fluorophe; H-P-FLUORO-PHE-OH; (S)-2-Amino-3-(4-fluorophenyl)propanoic acid; 4-Fluoro-Phe-OH; MFCD00063064; S-(-)-p-Fluorophenylalanine; para-fluorophenylalanine; p-Fluoro-L-phenylalanine; L-4-Fluoro-Phenylalanine; D,L-4-fluorophenylalanine; L-4-Fluoro-phe-OH; (2S)-2-amino-3-(4-fluorophenyl)propanoic acid; H-D-Phe(4-F)-OH; (S)-4-Fluorophenylalanine; 4-Fluoro-L-phenylalanine
Molecular FormulaC9H10O2N1F1
Molecular Weight183.18
Purity98%
Density1.3±0.1 g/cm3
Boiling Point313.3±32.0 °C at 760 mmHg
Melting Point~255 °C (dec.)
AppearanceWhite to off-white powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1132-68-9 |
| Catalog No. | 2A-9005791 |
| Chinese Name | L-4-氟苯丙氨酸 |
| Synonyms | L-4-FLUOROPHE; (2R)-2-Amino-3-(4-fluorophenyl)propanoic acid; D,L-p-fluorophenylalanine; L-4-F-Phe-OH; L-p-fluorophenylalanine; 4-Fluorophenylalanine; H-Phe(4-F)-OH; H-L-PHE(4-F)-OH; L-4-Fluorophenylalanine; 4-fluoroPhe; RARECHEM BK PT 0031; (2R)-2-amino-3-(4-fluorophenyl)propionic acid; D-4-Fluorophenylalanine; para-fluoro-l-phenylalanine; H-PHE(P-F)-OH; D-4-Fluorophe; H-P-FLUORO-PHE-OH; (S)-2-Amino-3-(4-fluorophenyl)propanoic acid; 4-Fluoro-Phe-OH; MFCD00063064; S-(-)-p-Fluorophenylalanine; para-fluorophenylalanine; p-Fluoro-L-phenylalanine; L-4-Fluoro-Phenylalanine; D,L-4-fluorophenylalanine; L-4-Fluoro-phe-OH; (2S)-2-amino-3-(4-fluorophenyl)propanoic acid; H-D-Phe(4-F)-OH; (S)-4-Fluorophenylalanine; 4-Fluoro-L-phenylalanine |
| Molecular Formula | C9H10O2N1F1 |
| Molecular Weight | 183.18 |
| Purity | 98 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 313.3±32.0 °C at 760 mmHg |
| Melting Point | ~255 °C (dec.) |
| Appearance | White to off-white powder |
| Storage Condition | Keep the receptacle sealed, stored in a cool, dry |
| Application | p-Fluoro-L-phenylalanine (4-fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) and can be used to study the regulation of this enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine |
| MDL Number | MFCD00063064 |
| SMILES | NC(Cc1ccc(F)cc1)C(=O)O |
| InChI Key | XWHHYOYVRVGJJY-QMMMGPOBSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/5791_1_1132_68_9.pdf |
| Bioactivity | p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (KD=0.26 μM)[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Luck LA, et al. Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli. Protein Sci. 2000;9(12):2573-2576. [2]. Hillas PJ, et al. A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines. Biochemistry. 1996;35(22):6969-6975. [3]. Luck LA, et al. Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli. Protein Sci. 2000;9(12):2573-2576. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 313.3±32.0 °C at 760 mmHg Melting Point ~255 °C (dec.) Molecular Formula C9H10FNO2 Molecular Weight 183.180 Flash Point 143.3±25.1 °C Exact Mass 183.069550 PSA 63.32000 LogP 1.16 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.555 InChIKey XWHHYOYVRVGJJY-QMMMGPOBSA-N SMILES NC(Cc1ccc(F)cc1)C(=O)O |
| Use of | p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (KD=0.26 μM)[1][2]. Properties Name 4-fluorophenyl-L-alanine Synonym More Synonyms 4-Fluoro-Phe-OH Biological Activity Description p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (KD=0.26 μM)[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Luck LA, et al. Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli. Protein Sci. 2000;9(12):2573-2576. [2]. Hillas PJ, et al. A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines. Biochemistry. 1996;35(22):6969-6975. [3]. Luck LA, et al. Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli. Protein Sci. 2000;9(12):2573-2576. Chemical & Physical Properties Molecular Formula C9H10FNO2 Exact Mass 183.069550 PSA 63.32000 Index of Refraction 1.555 InChIKey XWHHYOYVRVGJJY-QMMMGPOBSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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