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PIK 75

Name: PIK 75
Brand: 2A Biotech
SKU: 2A-9056891

CAS Number372196-67-3

Synonyms2-methyl-5-nitro-2,3-dihydro-phthalazine-1,4-dione; N'-[(E)-(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide; 2-Methyl-5-nitro-2,3-dihydro-phthalazin-1,4-dion; 8-Nitro-3-methyl-2,3-dihydro-1,4-phthalazindion; 1,4-Phthalazinedione,2,3-dihydro-2-methyl-5-nitro; N'-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide; 2'-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-1',2-dimethyl-5-nitrobenzenesulfonohydrazide; PIK-75 free base

Molecular FormulaC16H14BrN5O4S

Molecular Weight488.31 (free base basis)

Purity≥95 (HPLC)%

Density1.7±0.1 g/cm3

Appearancesolid

MSDSChinese English

Cat. No.: 2A-9056891 Purity: ≥95 (HPLC)%

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Quality Control of [ 372196-67-3 ] Purity: ≥95 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	372196-67-3
Catalog No.	2A-9056891
Chinese Name	PIK-75,游离
Synonyms	2-methyl-5-nitro-2,3-dihydro-phthalazine-1,4-dione; N'-[(E)-(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide; 2-Methyl-5-nitro-2,3-dihydro-phthalazin-1,4-dion; 8-Nitro-3-methyl-2,3-dihydro-1,4-phthalazindion; 1,4-Phthalazinedione,2,3-dihydro-2-methyl-5-nitro; N'-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide; 2'-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-1',2-dimethyl-5-nitrobenzenesulfonohydrazide; PIK-75 free base
Molecular Formula	C16H14BrN5O4S
Molecular Weight	488.31 (free base basis)
Purity	≥95 (HPLC)
Density	1.7±0.1 g/cm3
Appearance	solid
Storage Condition	-20°C, sealed, dry
Application	PIK-75 is a reversible DNA-PK and p110α-selective inhibitor that inhibits DNA-PK, p110α and p110γ with IC50 of 2, 5.8 and 76 nM respectively. PIK-75 inhibits p110α more than 200-fold more effectively
MDL Number	MFCD12546130
SMILES	[S](=O)(=O)(N(\N=C\c2[n]3c(nc2)ccc(c3)Br)C)c1c(ccc(c1)[N+](=O)[O-])C.Cl
InChI	1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;
InChI Key	VOUDEIAYNKZQKM-MYHMWQFYSA-N
NACRES Code	NA.28
UNSPSC	12352200
MSDS	msds/56891_1_372196_67_3.pdf
Transport Info	Product name: PIK-75, free

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PIK 75

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