CAS Number366017-09-6
SynonymsMubritinib (TAK 165); UNII-V734AZP9BR; Mubritinib,TAK 165,TAK165; (E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole; TAK 165; Mubritinib; cc-594; S2216_Selleck
Molecular FormulaC25H23F3N4O2
Molecular Weight468.47
Purity≥98 (HPLC)%
Density1.3±0.1 g/cm3
Boiling Point620.9±65.0 °C at 760 mmHg
Melting Point158.0 to 162.0 °C
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 366017-09-6 |
| Catalog No. | 2A-9056854 |
| Chinese Name | 木利替尼 |
| Synonyms | Mubritinib (TAK 165); UNII-V734AZP9BR; Mubritinib,TAK 165,TAK165; (E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole; TAK 165; Mubritinib; cc-594; S2216_Selleck |
| Molecular Formula | C25H23F3N4O2 |
| Molecular Weight | 468.47 |
| Purity | ≥98 (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 620.9±65.0 °C at 760 mmHg |
| Melting Point | 158.0 to 162.0 °C |
| Appearance | powder |
| Storage Condition | Store at +4°C |
| Application | Mubritinib (TAK-165) is a potent and selective EGFR2/HER2 inhibitor with an IC50 value of 6 nM. |
| PubChem ID | 329825777 |
| MDL Number | MFCD09954135 |
| SMILES | FC(F)(F)C1=CC=C(/C=C/C2=NC(COC3=CC=C(C=C3)CCCCN4C=CN=N4)=CO2)C=C1 |
| InChI | 1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+ |
| InChI Key | ZTFBIUXIQYRUNT-MDWZMJQESA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/56854_1_366017_09_6.pdf |
| Transport Info | Product name: Mulitinib |
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