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Doramapimod structure, CAS 285983-48-4

Doramapimod

CAS Number285983-48-4

Synonyms1kv2; BIRB796; 1-[3-tert-Butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(morpholin-4-yl)ethoxy]-1-naphthyl}urea; S1574_Selleck; Kinome_2137; 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea; L66J BO2- AT6N DOTJ& EMVM- ET5NNJ AR D1& CX1&1&1; doramapimod; BIRB 796; UNII-HO1A8B3YVV

Molecular FormulaC31H37N5O3

Molecular Weight527.66

Purity≥97 (HPLC)%

Density1.2±0.1 g/cm3

Boiling Point631.6±55.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9056307 Purity: ≥97 (HPLC)%
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Quality Control of [ 285983-48-4 ] Purity: ≥97 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number285983-48-4
Catalog No.2A-9056307
Chinese Name多马莫德
Synonyms1kv2; BIRB796; 1-[3-tert-Butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(morpholin-4-yl)ethoxy]-1-naphthyl}urea; S1574_Selleck; Kinome_2137; 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea; L66J BO2- AT6N DOTJ& EMVM- ET5NNJ AR D1& CX1&1&1; doramapimod; BIRB 796; UNII-HO1A8B3YVV
Molecular FormulaC31H37N5O3
Molecular Weight527.66
Purity≥97 (HPLC)
Density1.2±0.1 g/cm3
Boiling Point631.6±55.0 °C at 760 mmHg
Appearancesolid
Storage Condition-20°C
ApplicationDoramapimod is a highly potent p38α inhibitor with an IC50 of 4 nM and also inhibits B-Raf and Abl with an IC50 of 83 nM and 14.6 μM, respectively.
MDL NumberMFCD09752957
SMILESCC1=CC=C(N2C(NC(NC3=CC=C(OCCN4CCOCC4)C5=C3C=CC=C5)=O)=CC(C(C)(C)C)=N2)C=C1
InChI1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)
InChI KeyMVCOAUNKQVWQHZ-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC12352200
MSDSmsds/56307_1_285983_48_4.pdf
Transport InfoProduct Name: Doramapimod
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