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Sorafenib

Name: Sorafenib
Brand: 2A Biotech
SKU: 2A-9056298

CAS Number284461-73-0

SynonymsSORAFENIB TOLSYLATE; MFCD08235032; Bay 43-9006; Forafenib; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide; Sorafenib Free Base; Sorafenib; 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide; 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methyl-2-pyridinecarboxamide; BAY-43-900; Nexavar

Molecular FormulaC21H16ClF3N4O3

Molecular Weight464.82

Purity≥98 (HPLC)%

Density1.5±0.1 g/cm3

Boiling Point523.3±50.0 °C at 760 mmHg

Melting Point202-204°C

Appearancepowder

MSDSChinese English

Cat. No.: 2A-9056298 Purity: ≥98 (HPLC)%

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Quality Control of [ 284461-73-0 ] Purity: ≥98 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	284461-73-0
Catalog No.	2A-9056298
Chinese Name	索拉非尼
Synonyms	SORAFENIB TOLSYLATE; MFCD08235032; Bay 43-9006; Forafenib; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide; Sorafenib Free Base; Sorafenib; 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide; 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methyl-2-pyridinecarboxamide; BAY-43-900; Nexavar
Molecular Formula	C21H16ClF3N4O3
Molecular Weight	464.82
Purity	≥98 (HPLC)
Density	1.5±0.1 g/cm3
Boiling Point	523.3±50.0 °C at 760 mmHg
Melting Point	202-204°C
Appearance	powder
Storage Condition	-20°C Freezer
Application	Sorafenib (Bay 43-9006) is a potent multi-kinase inhibitor with IC50s of 6 nM, 20 nM and 22 nM for inhibiting Raf-1, B-Raf and VEGFR-3 respectively.
MDL Number	MFCD06411450
SMILES	FC(F)(F)c1c(ccc(c1)NC(=O)Nc2ccc(cc2)Oc3cc(ncc3)C(=O)NC)Cl
InChI	1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChI Key	MLDQJTXFUGDVEO-UHFFFAOYSA-N
NACRES Code	NA.77
UNSPSC	12352200
MSDS	msds/56298_1_284461_73_0.pdf
Transport Info	Product Name: Sorafenib

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