
CAS Number209394-46-7
Synonymsethyl-methyl-carbamic acid (R)-3-prop-2-ynylamino-indan-5-yl ester tartrate; TV-3326; Ladostigil tartrate; (3R)-3-(prop-2-ynylamino)-2,3,-dihydro-1H-indan-5-yl ethyl methyl carbamate tartrate; [(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate; R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N'-propargyl-1-aminoindan tartrate; (2R,3R)-2,3-dihydroxybutanedioic acid; R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N'-propargyl-1-aminoindan L-tartrate; TV-3219
Molecular FormulaC16H20N2O2.1/2C4H6O6
Molecular Weight347.39
Purity≥98 (HPLC)%
Boiling Point412.4ºC at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 209394-46-7 |
| Catalog No. | 2A-9055458 |
| Chinese Name | 乙基甲基-氨基甲酸 (3R)-2,3-二氢-3-(2-丙炔氨基)-1H-茚-5-基酯酒石酸盐 |
| Synonyms | ethyl-methyl-carbamic acid (R)-3-prop-2-ynylamino-indan-5-yl ester tartrate; TV-3326; Ladostigil tartrate; (3R)-3-(prop-2-ynylamino)-2,3,-dihydro-1H-indan-5-yl ethyl methyl carbamate tartrate; [(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate; R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N'-propargyl-1-aminoindan tartrate; (2R,3R)-2,3-dihydroxybutanedioic acid; R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N'-propargyl-1-aminoindan L-tartrate; TV-3219 |
| Molecular Formula | C16H20N2O2.1/2C4H6O6 |
| Molecular Weight | 347.39 |
| Purity | ≥98 (HPLC) |
| Boiling Point | 412.4ºC at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8°C, dry, sealed |
| Application | Ladostigil (TV-3326) hemitartrate is a dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO). The IC50 of MAO-B and AChE are 37.1 and 31.8 μM respectively. Ladotriester hemitart |
| MDL Number | MFCD22741393 |
| SMILES | N([C@@H]3CCc4c3cc(cc4)OC(=O)N(CC)C)CC#C.N([C@@H]1CCc2c1cc(cc2)OC(=O)N(CC)C)CC#C.O[C@H]([C@@H](O)C(=O)O)C(=O)O |
| InChI | 1S/2C16H20N2O2.C4H6O6/c2*1-4-10-17-15-9-7-12-6-8-13(11-14(12)15)20-16(19)18(3)5-2;5-1(3(7)8)2(6)4(9)10/h2*1,6,8,11,15,17H,5,7,9-10H2,2-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t2*15-;1-,2-/m111/s1 |
| InChI Key | PRLVBVAJMQZMJN-OGOSNNLPSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352200 |
| MSDS | msds/55458_1_209394_46_7.pdf |
| Transport Info | Product name: Ladostigil tartaric acid |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Mesosulfuron-methyl | 208465-21-8 | 2A-9055441 |
| 4-(1H-Pyrazol-5-yl)benzoic acid | 208511-67-5 | 2A-9055442 |
| 4-Chloroquinazolin-6-ylamine | 208533-37-3 | 2A-9055445 |
| 3-Bromo-4-isobutoxybenzonitrile | 208665-95-6 | 2A-9055446 |
| 3-Bromo-4-isobutoxybenzothioamide | 208665-96-7 | 2A-9055447 |
| 1-Naphthalenyl(1-propyl-1H-indol-3-yl)methanone | 209414-06-2 | 2A-9055460 |
| (1-Hexyl-1H-indol-3-yl)-1-naphthalenylmethanone | 209414-08-4 | 2A-9055462 |
| N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt | 209518-16-1 | 2A-9055464 |
| Anatibant | 209733-45-9 | 2A-9055474 |
| Entinostat | 209783-80-2 | 2A-9055475 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA