CAS Number119637-67-1
SynonymsEthyl (±)-2-((o-Methoxyphenoxy)methyl)-b-oxo-3-thiazolidinepropionate; Ethyl 3-{2-[(2-methoxyphenoxy)methyl]-1,3-thiazolidin-3-yl}-3-oxopropanoate; 3-Thiazolidinepropanoic acid, 2-[(2-methoxyphenoxy)methyl]-β-oxo-, ethyl ester; (±)-2-((2-Methoxyphenoxy)methyl)-b-oxo-3-thiazolidinepropanoic Acid Ethyl Ester; UNII:6Y556547YY
Molecular FormulaC16H21O5N1S1
Molecular Weight339.41
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point506.8±50.0 °C at 760 mmHg
Melting Point72-76ºC
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 119637-67-1 |
| Catalog No. | 2A-9051288 |
| Chinese Name | 莫吉司坦 |
| Synonyms | Ethyl (±)-2-((o-Methoxyphenoxy)methyl)-b-oxo-3-thiazolidinepropionate; Ethyl 3-{2-[(2-methoxyphenoxy)methyl]-1,3-thiazolidin-3-yl}-3-oxopropanoate; 3-Thiazolidinepropanoic acid, 2-[(2-methoxyphenoxy)methyl]-β-oxo-, ethyl ester; (±)-2-((2-Methoxyphenoxy)methyl)-b-oxo-3-thiazolidinepropanoic Acid Ethyl Ester; UNII:6Y556547YY |
| Molecular Formula | C16H21O5N1S1 |
| Molecular Weight | 339.41 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 506.8±50.0 °C at 760 mmHg |
| Melting Point | 72-76ºC |
| Storage Condition | Refrigerator |
| Application | Moguisteine (BBR-2173) is a novel peripheral non-narcotic antitussive compound. |
| MDL Number | MFCD00866839 |
| SMILES | CCOC(=O)CC(=O)N1CCSC1COc1ccccc1OC |
| InChI | InChI=1S/C16H21NO5S/c1-3-21-16(19)10-14(18)17-8-9-23-15(17)11-22-13-7-5-4-6-12(13)20-2/h4-7,15H,3,8-11H2,1-2H3 |
| InChI Key | WSYVIAQNTFPTBI-UHFFFAOYSA-N |
| MSDS | msds/51288_1_119637_67_1.pdf |
| Bioactivity | Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.Target: OthersMoguisteine is a novel peripheral nonnarcotic antitussive agent that has proved to be as active as codeine in several experimental models of induced cough in guinea-pigs and dogs. It acts neither through the opiate receptors nor on the cough centre, and its action is possibly mediated by the interaction with rapidly adapting irritant receptors along the tracheobronchial tree. In controlled clinical trials, moguisteine has been shown to be safe and to effectively reduce cough associated with such respiratory disorders as acute upper respiratory tract infection, chronic bronchitis, pulmonary fibrosis and malignancies [1, 2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Gallico, L., et al., Moguisteine: a novel peripheral non-narcotic antitussive drug. Br J Pharmacol, 1994. 112(3): p. 795-800. [2]. Gallico, L., et al., Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo. Eur Respir J, 1996. 9(3): p. 478-85. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 506.8±50.0 °C at 760 mmHg Melting Point 72-76ºC Molecular Formula C16H21NO5S Molecular Weight 339.407 Flash Point 260.3±30.1 °C Exact Mass 339.114044 PSA 90.37000 LogP 2.18 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.549 InChIKey WSYVIAQNTFPTBI-UHFFFAOYSA-N SMILES CCOC(=O)CC(=O)N1CCSC1COc1ccccc1OC Storage condition Refrigerator |
| Use of | Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.Target: OthersMoguisteine is a novel peripheral nonnarcotic antitussive agent that has proved to be as active as codeine in several experimental models of induced cough in guinea-pigs and dogs. It acts neither through the opiate receptors nor on the cough centre, and its action is possibly mediated by the interaction with rapidly adapting irritant receptors along the tracheobronchial tree. In controlled clinical trials, moguisteine has been shown to be safe and to effectively reduce cough associated with such respiratory disorders as acute upper respiratory tract infection, chronic bronchitis, pulmonary fibrosis and malignancies [1, 2]. Properties Name Moguisteine Synonym More Synonyms Moguisteine Biological Activity Description Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.Target: OthersMoguisteine is a novel peripheral nonnarcotic antitussive agent that has proved to be as active as codeine in several experimental models of induced cough in guinea-pigs and dogs. It acts neither through the opiate receptors nor on the cough centre, and its action is possibly mediated by the interaction with rapidly adapting irritant receptors along the tracheobronchial tree. In controlled clinical trials, moguisteine has been shown to be safe and to effectively reduce cough associated with such respiratory disorders as acute upper respiratory tract infection, chronic bronchitis, pulmonary fibrosis and malignancies [1, 2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Gallico, L., et al., Moguisteine: a novel peripheral non-narcotic antitussive drug. Br J Pharmacol, 1994. 112(3): p. 795-800. [2]. Gallico, L., et al., Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo. Eur Respir J, 1996. 9(3): p. 478-85. Chemical & Physical Properties Molecular Formula C16H21NO5S Exact Mass 339.114044 PSA 90.37000 Index of Refraction 1.549 InChIKey WSYVIAQNTFPTBI-UHFFFAOYSA-N Storage condition Refrigerator |
| Transport Info | Product Name: Moguisteine |
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