CAS Number119577-28-5
Synonyms(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; SN-38; SN38; 7-Ethyl-10-hydroxycamptothecine
Molecular FormulaC22H20O5N2
Molecular Weight392.41
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point810.3±65.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 119577-28-5 |
| Catalog No. | 2A-9051283 |
| Chinese Name | 7-乙基-10-羟基喜树碱 |
| Synonyms | (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; SN-38; SN38; 7-Ethyl-10-hydroxycamptothecine |
| Molecular Formula | C22H20O5N2 |
| Molecular Weight | 392.41 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 810.3±65.0 °C at 760 mmHg |
| Storage Condition | 2-8C |
| Application | 12-Ethyl-9-hydroxycamptothecin is a derivative of camptothecin. Camptothecin (CPT) is an alkaloid and a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 679nm[1]. |
| HTC | 2942000000 |
| MDL Number | MFCD06762720 |
| MSDS | msds/51283_1_119577_28_5.pdf |
| Use of | 12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Properties Name 7-ethyl-10-hydroxycamptothecin Synonym More Synonyms 12-Ethyl-9-hydroxycamptothecin Biological Activity Description 12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro 12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. References [1]. Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J Med Chem. 1995;38(3):395-401. Chemical & Physical Properties Molecular Formula C22H20N2O5 Exact Mass 392.137207 PSA 101.65000 Index of Refraction 1.738 Safety Information HS Code 2942000000 |
| Transport Info | Product name: 12-Ethyl-9-hydroxycamptothecin |
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