CAS Number119141-88-7
SynonymsS-enantiomer of omeprazole; Nexium; esomeprazolum; (-)-Omeprazole; (S)-(-)-Omeprazole; Esomeprazole (INN); perprazole; (S)-Omeprazole; MFCD06798050; EINECS 201-212-8; 6-Methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole; (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; Esomeprazole; 5-Methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole; esomeprazol; (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole; (S)-Esomeprazole; UNII-N3PA6559FT; 6-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole; 5-methoxy-2-(((4-methoxy-3,5-dimethylpyri
Molecular FormulaC17H19O3N3S1
Molecular Weight345.42
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point600.0±60.0 °C at 760 mmHg
AppearanceWhite to yellow to gray powder or crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 119141-88-7 |
| Catalog No. | 2A-9051242 |
| Chinese Name | 埃索美拉唑 |
| Synonyms | S-enantiomer of omeprazole; Nexium; esomeprazolum; (-)-Omeprazole; (S)-(-)-Omeprazole; Esomeprazole (INN); perprazole; (S)-Omeprazole; MFCD06798050; EINECS 201-212-8; 6-Methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole; (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; Esomeprazole; 5-Methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole; esomeprazol; (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole; (S)-Esomeprazole; UNII-N3PA6559FT; 6-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole; 5-methoxy-2-(((4-methoxy-3,5-dimethylpyri |
| Molecular Formula | C17H19O3N3S1 |
| Molecular Weight | 345.42 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 600.0±60.0 °C at 760 mmHg |
| Appearance | White to yellow to gray powder or crystal |
| Storage Condition | Room temperature, sealed, dry |
| Application | Esomeprazole ((S)-omeprazole) is a potent oral proton pump inhibitor that reduces acid secretion by inhibiting H+,K+-ATPase in gastric parietal cells. Esomeprazole has the potential to be used in the |
| HTC | 2933990090 |
| MDL Number | MFCD05662029 |
| SMILES | COc1ccc2nc(S(=O)Cc3ncc(C)c(OC)c3C)[nH]c2c1 |
| InChI | InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m1/s1 |
| InChI Key | SUBDBMMJDZJVOS-DEOSSOPVSA-N |
| MSDS | msds/51242_1_119141_88_7.pdf |
| Use of | Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3]. Properties Name esomeprazole Synonym More Synonyms Esomeprazole Biological Activity Description Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3]. Related Catalog Research Areas >> Cancer Research Areas >> Endocrinology Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump H+, K+-ATPase[1][2] References [1]. Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46. [2]. Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16. [3]. Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. Chemical & Physical Properties Molecular Formula C17H19N3O3S Exact Mass 345.114716 PSA 96.31000 Index of Refraction 1.669 InChIKey SUBDBMMJDZJVOS-DEOSSOPVSA-N Safety Information Hazard Codes Xn HS Code 2933990090 Synthetic Route ufiprazole CAS#:73590-85-9 Esomeprazole CAS#:119141-88-7 Literature: Che, Guoyong; Xiang, Jing; Tian, Tian; Huang, Qingfei; Cun, Linfeng; Liao, Jian; Wang, Qiwei; Zhu, Jin; Deng, Jingen Tetrahedron Asymmetry, 2012 , vol. 23, # 6-7 p. 457 - 460 ufiprazole CAS#:73590-85-9 (+)-omeprazole CAS#:119141-89-8 Esomeprazole CAS#:119141-88-7 10-camphorsulfo... CAS#:21286-54-4 omeprazole CAS#:73590-58-6 Esomeprazole CAS#:119141-88-7 Precursor & DownStream Precursor 5 CAS#:73590-85-9 ufiprazole CAS#:21286-54-4 10-camphorsulfo... CAS#:73590-58-6 omeprazole CAS#:1080503-75-8 (-)-menthyl (S)... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in API & Advanced Intermediates | ||
|---|---|---|
| (RS)-Duloxetine hydrochloride | 116817-11-9 | 2A-9051057 |
| Azithromycin dihydrate | 117772-70-0 | 2A-9051130 |
| Desmethyl rabeprazole thioether | 117976-91-7 | 2A-9051150 |
| Ofloxacin hydrochloride | 118120-51-7 | 2A-9051163 |
| Nebivolol | 118457-14-0 | 2A-9051198 |
| Diclofenac epolamine | 119623-66-4 | 2A-9051287 |
| Clopidogrel camphorsulfonate | 120202-68-8 | 2A-9051329 |
| Azithromycin monohydrate | 121470-24-4 | 2A-9051424 |
| (+)-Tramadol | 123154-38-1 | 2A-9051546 |
| Topotecan acetate | 123948-88-9 | 2A-9051602 |
| Browse all API & Advanced Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS