
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 113694-64-7 |
| Catalog No. | 2A-9050774 |
| Chinese Name | 2-[6-[双(羧甲基)氨基]-5-[2-[2-[双(羧甲基)氨基]-5-甲基苯氧基]乙氧基]-2-苯并呋喃基]-5-恶唑羧酸五钾盐 |
| Synonyms | FURA 2 PENTAPOTASSIUM SALT; Fura-2,pentapotassium salt; MFCD00083328 |
| Molecular Formula | C29H22K5N3O14 |
| Molecular Weight | 831.99 |
| Purity | ≥90 (HPLC) |
| Boiling Point | 983.5ºC at 760 mmHg |
| Appearance | solid |
| Storage Condition | Store airtight in a cool, dry warehouse. Refrigera |
| Application | Furan-2 Pentapotassium is a calibrated fluorescent dye that can be used for intracellular calcium imaging with a Kd value of 140 nM. The emission wavelength of pentapotassium furan-2 is 510 nm, and th |
| PubChem ID | 57647616 |
| MDL Number | MFCD00083328 |
| SMILES | [K+].[K+].[K+].[K+].[K+].Cc1ccc(N(CC([O-])=O)CC([O-])=O)c(OCCOc2cc3cc(oc3cc2N(CC([O-])=O)CC([O-])=O)-c4ncc(o4)C([O-])=O)c1 |
| InChI | 1S/C29H27N3O14.5K/c1-15-2-3-17(31(11-24(33)34)12-25(35)36)20(6-15)43-4-5-44-21-7-16-8-22(28-30-10-23(46-28)29(41)42)45-19(16)9-18(21)32(13-26(37)38)14-27(39)40;;;;;/h2-3,6-10H,4-5,11-14H2,1H3,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42);;;;;/q;5*+1/p-5 |
| InChI Key | HQKWBBCTCLUGSX-UHFFFAOYSA-I |
| NACRES Code | NA.32 |
| UNSPSC | 12171500 |
| Hazard Symbols | transportation |
| MSDS | msds/50774_1_113694_64_7.pdf |
| Bioactivity | Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro Fura-2 pentapotassium (10 μM, 2 min) can be used to detect changes in the concentration of calcium ions in neutrophils of heparinized peripheral blood[1]. Fura-2 pentapotassium (10 μM, 5 min) can be used as a calcium probe to assess the distribution of calcium ions within heart mitochondria without affecting the activity of it in rat[2]. References [1]. Omar Rafael Alemán, et al. The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. Front Immunol. 2021 May 13;12:657393. doi: 10.3389/fimmu.2021.657393. [2]. James G. McCormack, et al. Studies on mitochondrial Ca2+-transport and matrix Ca2+ using fura-2-loaded rat heart mitochondria. Biochim Biophys Acta. 1989 Mar 23;973(3):420-7. Chemical & Physical Properties Boiling Point 983.5ºC at 760 mmHg Molecular Formula C29H22K5N3O14 Molecular Weight 831.98800 Flash Point 548.6ºC Exact Mass 830.92900 PSA 264.76000 Vapour Pressure 0mmHg at 25°C InChIKey DMJNHSMTLKZJJX-UHFFFAOYSA-N SMILES Cc1ccc(N(CC(=O)O)CC(=O)O)c(OCCOc2cc3cc(-c4ncc(C(=O)O)o4)oc3cc2N(CC(=O)O)CC(=O)O)c1.[K] |
| Use of | Properties Name Fura 2 pentapotassium salt Synonym More Synonyms Fura 2 pentapotassium salt Biological Activity Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [2]. James G. McCormack, et al. Studies on mitochondrial Ca2+-transport and matrix Ca2+ using fura-2-loaded rat heart mitochondria. Biochim Biophys Acta. 1989 Mar 23;973(3):420-7. Chemical & Physical Properties Molecular Formula C29H22K5N3O14 Exact Mass 830.92900 PSA 264.76000 InChIKey DMJNHSMTLKZJJX-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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