CAS Number253449-04-6
Synonyms1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(dimethylamino)-2-propanol; 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol; 1-(3,6-Dibromo-carbazol-9-yl)-3-dimethylamino-propan-2-ol; 1-(3,6-dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol; Wiskostatin; 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
Molecular FormulaC17H18Br2N2O
Molecular Weight426.15
Purity≥98 (HPLC)%
Density1.6±0.1 g/cm3
Boiling Point320.2±22.0 °C at 760 mmHg
Melting Point153-155ºC
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 253449-04-6 |
| Catalog No. | 2A-9000505 |
| Chinese Name | 1-(3,6-二溴-9h-咔唑-9-基)-3-(二甲基氨基)-2-丙醇 |
| Synonyms | 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(dimethylamino)-2-propanol; 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol; 1-(3,6-Dibromo-carbazol-9-yl)-3-dimethylamino-propan-2-ol; 1-(3,6-dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol; Wiskostatin; 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol |
| Molecular Formula | C17H18Br2N2O |
| Molecular Weight | 426.15 |
| Purity | ≥98 (HPLC) |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 320.2±22.0 °C at 760 mmHg |
| Melting Point | 153-155ºC |
| Appearance | powder |
| Storage Condition | 2-8°C |
| Application | Wiskottatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound and irreversible decrease in c |
| HTC | 2933990090 |
| PubChem ID | 329830469 |
| MDL Number | MFCD00218393 |
| SMILES | CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 |
| InChI | 1S/C17H18Br2N2O/c1-20(2)9-13(22)10-21-16-5-3-11(18)7-14(16)15-8-12(19)4-6-17(15)21/h3-8,13,22H,9-10H2,1-2H3 |
| InChI Key | XUBJEDZHBUPBKL-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | Transport |
| MSDS | msds/505_1_253449_04_6.pdf |
| Bioactivity | Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1]. Related Catalog Signaling Pathways >> Cytoskeleton >> Arp2/3 Complex Research Areas >> Neurological Disease References [1]. Guerriero CJ, et al. N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels. Am J Physiol Cell Physiol. 2007;292(4):C1562-C1566. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 320.2±22.0 °C at 760 mmHg Melting Point 153-155ºC Molecular Formula C17H18Br2N2O Molecular Weight 426.146 Flash Point 147.4±22.3 °C Exact Mass 423.978577 PSA 28.40000 LogP 5.65 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.657 InChIKey XUBJEDZHBUPBKL-UHFFFAOYSA-N SMILES CN(C)CC(O)Cn1c2ccc(Br)cc2c2cc(Br)ccc21 Storage condition 2-8°C |
| Use of | Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1]. Properties Name 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol Synonym More Synonyms Wiskostatin Biological Activity Description Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1]. Related Catalog Research Areas >> Neurological Disease References [1]. Guerriero CJ, et al. N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels. Am J Physiol Cell Physiol. 2007;292(4):C1562-C1566. Chemical & Physical Properties Molecular Formula C17H18Br2N2O Exact Mass 423.978577 PSA 28.40000 Index of Refraction 1.657 InChIKey XUBJEDZHBUPBKL-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (Wiskostatin) IMDG Code: TOXIC SOLID, ORGANIC, N.O.S. (Wiskostatin) International air transport hazard regulations: Toxic solid, organic, n.o.s. (Wiskostatin) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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