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N-Hydroxysulfosuccinimide sodium salt structure, CAS 106627-54-7

N-Hydroxysulfosuccinimide sodium salt

CAS Number106627-54-7

Synonyms3-Pyrrolidinesulfonic acid, 1-hydroxy-2,5-dioxo-, sodium salt (1:1); Sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate; Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid sodium salt; N-Hydroxysulfosuccinimide sodiumsalt; Sodium 1-hydroxy-2,5-dioxo-3-pyrrolidinesulfonate; sodium,1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate; N-Hydroxysulfosuccinimide Sodium Salt; MFCD00217065

Molecular FormulaC4H4NNaO6S

Molecular Weight217.13

Purity≥98 (HPLC)%

Density

Boiling Point

Melting Point250 °C (dec.)(lit.)

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9050282 Purity: ≥98 (HPLC)%
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Quality Control of [ 106627-54-7 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number106627-54-7
Catalog No.2A-9050282
Chinese NameN-羟基琥珀酰亚胺磺酸钠盐
Synonyms3-Pyrrolidinesulfonic acid, 1-hydroxy-2,5-dioxo-, sodium salt (1:1); Sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate; Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid sodium salt; N-Hydroxysulfosuccinimide sodiumsalt; Sodium 1-hydroxy-2,5-dioxo-3-pyrrolidinesulfonate; sodium,1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate; N-Hydroxysulfosuccinimide Sodium Salt; MFCD00217065
Molecular FormulaC4H4NNaO6S
Molecular Weight217.13
Purity≥98 (HPLC)
Melting Point250 °C (dec.)(lit.)
Appearancepowder
Storage ConditionKeep the container sealed and stored in a cool, dr
ApplicationN-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).
HTC2925190090
PubChem ID57651582
MDL NumberMFCD00043100
SMILES[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O
InChI1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1
InChI KeyRPENMORRBUTCPR-UHFFFAOYSA-M
Beilstein/REAXYS6359129
NACRES CodeNA.22
UNSPSC12352005
Hazard Symbolstransportation
MSDSmsds/50282_1_106627_54_7.pdf
BioactivityN-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Non-cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. References [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. Chemical & Physical Properties Melting Point 250 °C (dec.)(lit.) Molecular Formula C4H4NNaO6S Molecular Weight 217.132 Exact Mass 216.965698 PSA 123.19000 InChIKey RPENMORRBUTCPR-UHFFFAOYSA-M SMILES O=C1CC(S(=O)(=O)[O-])C(=O)N1O.[Na+] Storage condition 0-6°C
Use ofN-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Properties Articles107 Name N-Hydroxysulfosuccinimide sodium salt Synonym More Synonyms N-Hydroxysulfosuccinimide sodium Biological Activity Description N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Non-cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. References [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. Chemical & Physical Properties Molecular Formula C4H4NNaO6S Exact Mass 216.965698 PSA 123.19000 InChIKey RPENMORRBUTCPR-UHFFFAOYSA-M
Tax Rebate9.0%
SupervisionNone MFN tariff: 6.5% Ordinary tariff: 30.0%
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: - International Maritime Transport Danger Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Danger Regulations: - International Maritime Transport Danger Regulations: - 14.4 Package group European Land Transport Danger Regulations: - International Maritime Transport Danger Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Transport Danger Regulations Marine pollutants (yes/no): No 14.6 Special reminder to users No data available If applicable, the chemical meets the requirements of the Regulations on the Safety Management of Hazardous Chemicals.
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