CAS Number104821-25-2
Synonymsdihydroethidium; MFCD00077335; 5,6-dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine; 5-Ethyl-6-phenyl-5,6-dihydro-3,8-phenanthridinediamine
Molecular FormulaC21H21N3
Molecular Weight315.41
Purity≥95 (HPLC)%
Density1.2±0.1 g/cm3
Boiling Point580.4±50.0 °C at 760 mmHg
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 104821-25-2 |
| Catalog No. | 2A-9050143 |
| Chinese Name | 二氢乙锭 |
| Synonyms | dihydroethidium; MFCD00077335; 5,6-dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine; 5-Ethyl-6-phenyl-5,6-dihydro-3,8-phenanthridinediamine |
| Molecular Formula | C21H21N3 |
| Molecular Weight | 315.41 |
| Purity | ≥95 (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 580.4±50.0 °C at 760 mmHg |
| Appearance | solid |
| Water Solubility | acetonitrile: soluble |
| Storage Condition | Store airtight in a cool, dry warehouse. Refrigera |
| Application | Dihydroethidium (Hydroethidine; PD-MY 003) is a peroxide indicator that fluoresces blue in the cytoplasm until oxidized. |
| HTC | 2933990090 |
| MDL Number | MFCD00077335 |
| SMILES | Nc1c2c(cnc1)c3c(cc(cc3)N)C(C2CC)c4ccccc4 |
| InChI | 1S/C21H21N3/c1-2-15-20(13-6-4-3-5-7-13)17-10-14(22)8-9-16(17)18-11-24-12-19(23)21(15)18/h3-12,15,20H,2,22-23H2,1H3 |
| InChI Key | ZDWPSSBKIMIPMY-UHFFFAOYSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12161505 |
| Hazard Symbols | transportation |
| MSDS | msds/50143_1_104821_25_2.pdf |
| Bioactivity | Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Zielonka J, et al. Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses. J Biol Chem. 2012 Jan 27;287(5):2984-95. [2]. Kwong C, et al. Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. J Immunol. 2011 Feb 1;186(3):1781-9. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 580.4±50.0 °C at 760 mmHg Molecular Formula C21H21N3 Molecular Weight 315.411 Flash Point 299.5±24.9 °C Exact Mass 315.173553 PSA 55.92000 LogP 3.06 Vapour Pressure 0.0±1.6 mmHg at 25°C Index of Refraction 1.680 InChIKey XYJODUBPWNZLML-UHFFFAOYSA-N SMILES CCN1c2cc(N)ccc2-c2ccc(N)cc2C1c1ccccc1 Storage condition −20°C Water Solubility acetonitrile: soluble |
| Use of | Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red. Properties Articles340 Name Dihydroethidium Synonym More Synonyms Dihydroethidium Biological Activity Description Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Zielonka J, et al. Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses. J Biol Chem. 2012 Jan 27;287(5):2984-95. [2]. Kwong C, et al. Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. J Immunol. 2011 Feb 1;186(3):1781-9. Chemical & Physical Properties Molecular Formula C21H21N3 Exact Mass 315.173553 PSA 55.92000 Index of Refraction 1.680 InChIKey XYJODUBPWNZLML-UHFFFAOYSA-N Water Solubility acetonitrile: soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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