![1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride structure, CAS 84484-78-6](/structures/60000/49052_1_84484_78_6.png)
CAS Number84484-78-6
SynonymsMFCD03411585; Didesmethylsibutramine hydrochloride; Bts 54 505; Cyclobutanemethanamine, 1-(4-chlorophenyl)-α-(2-methylpropyl)-, hydrochloride (1:1); UNII:XJH8PK8XYH; 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutan-1-amine hydrochloride (1:1); Cyclobutanemethanamine, 1-(4-chlorophenyl)-α-(2-methylpropyl)-, hydrochloride; 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butanamine hydrochloride (1:1); 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride
Molecular FormulaC15H23Cl2N
Molecular Weight302.28
Purity98.00%
Boiling Point337.9ºC at 760 mmHg
Melting Point160 - 166°C (lit.)
AppearanceWhite to off-white solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 84484-78-6 |
| Catalog No. | 2A-9049052 |
| Chinese Name | 1-[1-(4-氯苯基)环丁基]-3-甲基丁胺盐酸盐 |
| Synonyms | MFCD03411585; Didesmethylsibutramine hydrochloride; Bts 54 505; Cyclobutanemethanamine, 1-(4-chlorophenyl)-α-(2-methylpropyl)-, hydrochloride (1:1); UNII:XJH8PK8XYH; 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutan-1-amine hydrochloride (1:1); Cyclobutanemethanamine, 1-(4-chlorophenyl)-α-(2-methylpropyl)-, hydrochloride; 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butanamine hydrochloride (1:1); 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride |
| Molecular Formula | C15H23Cl2N |
| Molecular Weight | 302.28 |
| Purity | 98.00 |
| Boiling Point | 337.9ºC at 760 mmHg |
| Melting Point | 160 - 166°C (lit.) |
| Appearance | White to off-white solid |
| Storage Condition | Desiccate at RT |
| Application | Didesmethylsibutramine (BTS 54-505) hydrochloride is the primary amine metabolite of Sibutramine, an antidepressant and anti-obesity compound. Didesmethylsibutramine inhibits NMDA-induced activity. Di |
| PubChem ID | 10243740 |
| MDL Number | MFCD07363916 |
| SMILES | Clc1ccc(cc1)C2(CCC2)C(NC)CC(C)C.Cl |
| InChI | 1S/C16H24ClN.ClH/c1-12(2)11-15(18-3)16(9-4-10-16)13-5-7-14(17)8-6-13;/h5-8,12,15,18H,4,9-11H2,1-3H3;1H |
| InChI Key | OUVFHVJVFLFXPQ-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/49052_1_84484_78_6.pdf |
| Bioactivity | Didesmethylsibutramine (BTS 54-505) hydrochloride is the primary amine metabolite of Sibutramine (antidepressant and anti-obesity agent). Didesmethylsibutramine hydrochloride inhibits NMDA-evoked activity. Didesmethylsibutramine hydrochloride is also a reuptake inhibitor. Didesmethylsibutramine hydrochloride induces thermogenesis[1][2]. Related Catalog Research Areas >> Metabolic Disease References [1]. Liu YL, et al. Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine. Int J Obes Relat Metab Disord. 2002 Sep;26(9):1245-53. [2]. Scott G, et al. The effects of BTS 54,505, a metabolite of sibutramine, on monoamine and excitatory amino acid-evoked responses in the rat dorsolateral geniculate nucleus in vivo. Br J Pharmacol. 1994 Jan;111(1):97-102. Chemical & Physical Properties Boiling Point 337.9ºC at 760 mmHg Melting Point 160 - 166°C (lit.) Molecular Formula C15H23Cl2N Molecular Weight 288.26 Flash Point 195.1ºC Exact Mass 287.120758 PSA 26.02000 LogP 5.63740 InChIKey KHRVYINTXCWNRF-UHFFFAOYSA-N SMILES CC(C)CC(N)C1(c2ccc(Cl)cc2)CCC1.Cl Storage condition Desiccate at RT |
| Use of | Didesmethylsibutramine (BTS 54-505) hydrochloride is the primary amine metabolite of Sibutramine (antidepressant and anti-obesity agent). Didesmethylsibutramine hydrochloride inhibits NMDA-evoked activity. Didesmethylsibutramine hydrochloride is also a reuptake inhibitor. Didesmethylsibutramine hydrochloride induces thermogenesis[1][2]. Properties Name 1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine,hydrochloride Synonym More Synonyms BTS 54-505 hydrochloride Biological Activity Description Didesmethylsibutramine (BTS 54-505) hydrochloride is the primary amine metabolite of Sibutramine (antidepressant and anti-obesity agent). Didesmethylsibutramine hydrochloride inhibits NMDA-evoked activity. Didesmethylsibutramine hydrochloride is also a reuptake inhibitor. Didesmethylsibutramine hydrochloride induces thermogenesis[1][2]. Related Catalog Research Areas >> Metabolic Disease References [1]. Liu YL, et al. Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine. Int J Obes Relat Metab Disord. 2002 Sep;26(9):1245-53. [2]. Scott G, et al. The effects of BTS 54,505, a metabolite of sibutramine, on monoamine and excitatory amino acid-evoked responses in the rat dorsolateral geniculate nucleus in vivo. Br J Pharmacol. 1994 Jan;111(1):97-102. Chemical & Physical Properties Exact Mass 287.120758 PSA 26.02000 LogP 5.63740 InChIKey KHRVYINTXCWNRF-UHFFFAOYSA-N Storage condition Desiccate at RT |
| Transport Info | Product Name: BTS 54-505 hydrochloride |
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