CAS Number83207-58-3
SynonymsAstragalus Polysaccharides; ASTRAGALOSIDE; ASTRAGALOSIDE IV(RG); Astrasieversianin XIV; Astragaloside IV; Astragaloside A; cyclosiversioside F; cyclosieversioside F
Molecular FormulaC41H68O14
Molecular Weight784.98
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point895.7±65.0 °C at 760 mmHg
Melting Point284-286ºC
Appearancewhite powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 83207-58-3 |
| Catalog No. | 2A-9048863 |
| Chinese Name | 黄芪甲苷A(黄芪甲苷 IV) |
| Synonyms | Astragalus Polysaccharides; ASTRAGALOSIDE; ASTRAGALOSIDE IV(RG); Astrasieversianin XIV; Astragaloside IV; Astragaloside A; cyclosiversioside F; cyclosieversioside F |
| Molecular Formula | C41H68O14 |
| Molecular Weight | 784.98 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 895.7±65.0 °C at 760 mmHg |
| Melting Point | 284-286ºC |
| Appearance | white powder |
| Storage Condition | 2~8℃ |
| Application | Astragaloside A is the main active component of Astragalus in traditional Chinese medicine; it has been widely used in the treatment of ischemic diseases. |
| HTC | 2932999099 |
| PubChem ID | 135079149 |
| MDL Number | MFCD30207849 |
| SMILES | CC(C)(O)C1CCC(C)(C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C5C(C)(C)C(OC6OCC(O)C(O)C6O)CCC56CC46CCC23C)O1 |
| InChI | InChI=1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27?,28-,29+,30?,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1 |
| InChI Key | QMNWISYXSJWHRY-AUJDEUPOSA-N |
| MSDS | msds/48863_1_83207_58_3.pdf |
| Use of | Properties Name astragaloside IV Synonym More Synonyms Astragaloside A Biological Activity Related Catalog Signaling Pathways >> Others >> Others Natural Products >> Terpenoids and Glycosides Research Areas >> Cancer References [2]. Lu M, et al. Astragaloside IV protects against cardiac hypertrophy via inhibiting the Ca2+/CaN signaling pathway. Planta Med. 2014 Jan;80(1):63-9. [3]. Wang Q, et al. Astragalosides IV inhibits high glucose-induced cell apoptosis through HGF activation in cultured human tubular epithelial cells. Ren Fail. 2014 Apr;36(3):400-6. [4]. Zhang A, et al. Astragaloside IV inhibits progression of lung cancer by mediating immune function of Tregs and CTLs by interfering with IDO. J Cancer Res Clin Oncol. 2014 Nov;140(11):1883-90. [5]. Xu W, et al. Astragaloside IV ameliorates renal fibrosis via the inhibition of mitogen-activated protein kinases and antiapoptosis in vivo and in vitro. J Pharmacol Exp Ther. 2014 Sep;350(3):552-62. Chemical & Physical Properties Molecular Formula C41H68O14 Exact Mass 784.460938 PSA 228.22000 Index of Refraction 1.621 InChIKey QMNWISYXSJWHRY-AUJDEUPOSA-N Storage condition 2~8℃ Safety Information Hazard Codes Xi HS Code 2932999099 Synthetic Route astragaloside VII CAS#:84687-46-7 Astragaloside A CAS#:83207-58-3 Cycloastragenol... CAS#:86764-12-7 Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 2 p. 716 - 722 Astragaloside VI CAS#:84687-45-6 Astragaloside A CAS#:83207-58-3 Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 2 p. 709 - 715 Astrasieversian... CAS#:86764-11-6 Astragaloside A CAS#:83207-58-3 Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 2 p. 698 - 708 Precursor & DownStream Precursor 7 CAS#:84687-46-7 astragaloside VII CAS#:84687-45-6 Astragaloside VI CAS#:86764-11-6 Astrasieversian... CAS#:84676-88-0 Isoastragaloside I DownStream 2 CAS#:84605-18-5 Cycloastragenol CAS#:86764-12-7 Cycloastragenol... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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