| Chemical & Physical Properties | |
|---|---|
| CAS Number | 83104-85-2 |
| Catalog No. | 2A-9048851 |
| Chinese Name | 钙荧光探针 QUIN 2-AM |
| Synonyms | MFCD00010285; Quin-2 acetoxymethyl ester; quin 2 am; Quin-2AM |
| Molecular Formula | C38H43N3O18 |
| Molecular Weight | 829.75700 |
| Purity | 98.00 |
| Density | 1.36 g/cm3 |
| Boiling Point | 865.6ºC at 760 mmHg |
| Appearance | liquid |
| Storage Condition | Sealed with argon gas and stored dry and protected |
| Application | Quin-2AM is a fluorescent chelator of Ca2+ with high affinity for calcium. |
| EINECS | 200-664-3 |
| PubChem ID | 6578018 |
| MDL Number | MFCD00036969 |
| SMILES | CC(=O)OCOC(=O)CCc1cc2c(Oc3cc(OCOC(C)=O)c(CCC(=O)OCOC(C)=O)cc3C24OC(=O)c5cc(ccc45)C(=O)OCOC(C)=O)cc1OCOC(C)=O |
| InChI | 1S/C42H40O21/c1-22(43)52-17-57-34-15-36-32(13-27(34)7-10-38(48)59-19-54-24(3)45)42(31-9-6-29(12-30(31)41(51)63-42)40(50)61-21-56-26(5)47)33-14-28(8-11-39(49)60-20-55-25(4)46)35(16-37(33)62-36)58-18-53-23(2)44/h6,9,12-16H,7-8,10-11,17-21H2,1-5H3 |
| InChI Key | NTECHUXHORNEGZ-UHFFFAOYSA-N |
| NACRES Code | NA.47 |
| UNSPSC | 12171500 |
| Hazard Symbols | transportation |
| MSDS | msds/48851_1_83104_85_2.pdf |
| Bioactivity | Quin-2AM is a fluorecent Ca2+ chelator, with high affinity for calcium. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Biochemical Assay Reagents In Vitro Quin-2AM (20 µM) or A23187 (20 µM) drastically activate mTF activity without detectable effect on mTF synthesis; both of which show that sustained functional upregulation during 24 h culture does not enhance Marcks expression. Quin-2AM (20 µM) changes the non-detectable Marcks level in 24 h cultures[1]. References [1]. Chu AJ, et al. Possible role of Marcks in the cellular modulation of monocytic tissue factor-initiated hypercoagulation. Br J Haematol. 2002 Aug;118(2):569-76. Chemical & Physical Properties Density 1.36 g/cm3 Boiling Point 865.6ºC at 760 mmHg Molecular Formula C38H43N3O18 Molecular Weight 829.75700 Flash Point 477.3ºC Exact Mass 829.25400 PSA 248.23000 LogP 1.99880 Index of Refraction 1.576 InChIKey ANRZUBSJAOAXHS-UHFFFAOYSA-N SMILES COc1cc(N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)c2nc(COc3cc(C)ccc3N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)ccc2c1 |
| Use of | Quin-2AM is a fluorecent Ca2+ chelator, with high affinity for calcium. Properties Name acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[[8-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-6-methoxyquinolin-2-yl]methoxy]-4-methylanilino]acetate Synonym More Synonyms Quin 2-AM Biological Activity Description Quin-2AM is a fluorecent Ca2+ chelator, with high affinity for calcium. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Biochemical Assay Reagents In Vitro Quin-2AM (20 µM) or A23187 (20 µM) drastically activate mTF activity without detectable effect on mTF synthesis; both of which show that sustained functional upregulation during 24 h culture does not enhance Marcks expression. Quin-2AM (20 µM) changes the non-detectable Marcks level in 24 h cultures[1]. References [1]. Chu AJ, et al. Possible role of Marcks in the cellular modulation of monocytic tissue factor-initiated hypercoagulation. Br J Haematol. 2002 Aug;118(2):569-76. Chemical & Physical Properties Molecular Formula C38H43N3O18 Exact Mass 829.25400 PSA 248.23000 LogP 1.99880 Index of Refraction 1.576 InChIKey ANRZUBSJAOAXHS-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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