CAS Number80724-20-5
Synonyms6-TRITC; T3163_SIAL; BIT3022; 5(6)-Tetramethylrhodamine isothiocyanate; Tetramethylrhodamine-6-isothiocyanate; Tetramethylrhodamine isothiocyanate
Molecular FormulaC25H21N3O3S
Molecular Weight443.52
Purity98.00%
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 80724-20-5 |
| Catalog No. | 2A-9048523 |
| Chinese Name | 四甲基罗丹明-6-异硫氰酸 |
| Synonyms | 6-TRITC; T3163_SIAL; BIT3022; 5(6)-Tetramethylrhodamine isothiocyanate; Tetramethylrhodamine-6-isothiocyanate; Tetramethylrhodamine isothiocyanate |
| Molecular Formula | C25H21N3O3S |
| Molecular Weight | 443.52 |
| Purity | 98.00 |
| Appearance | powder |
| Storage Condition | 2~8°C |
| Application | Tetramethylrhodamine-6-isothiocyanate is an effective fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as a probe of haptenized proteins/peptides for the study of contact allergie |
| PubChem ID | 24900112 |
| MDL Number | MFCD00063517 |
| SMILES | CN(C)c1ccc2c(OC3=C\C(C=CC3=C2c4cc(ccc4C([O-])=O)N=C=S)=[N+](/C)C)c1 |
| InChI | 1S/C25H21N3O3S/c1-27(2)16-6-9-19-22(12-16)31-23-13-17(28(3)4)7-10-20(23)24(19)21-11-15(26-14-32)5-8-18(21)25(29)30/h5-13H,1-4H3 |
| InChI Key | OBYNJKLOYWCXEP-UHFFFAOYSA-N |
| NACRES Code | NA.47 |
| UNSPSC | 12171500 |
| Hazard Symbols | transportation |
| MSDS | msds/48523_1_80724_20_5.pdf |
| Bioactivity | Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro Tetramethylrhodamine-6-isothiocyanate is relatively photostable and robust toward pH changes[1]. Tetramethylrhodamine-6-isothiocyanate as an extreme sensitizer induces a massive cell proliferation and gave an EC3 value of 0.92 mM (0.040%) in the murine LLNA (local lymph node assay)[1]. Tetramethylrhodamine-6-isothiocyanate (1.0 mg; 2h) can used as fluorescence probe for confocal imaging in Fe3O4@PDA incubated living cells[2]. References [1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203. [2]. Yue Q ,et al . A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures. J Mater Chem B. 2013 Nov 28;1(44):6085-6093. Chemical & Physical Properties Molecular Formula C25H21N3O3S Molecular Weight 443.51800 Exact Mass 443.13000 PSA 104.20000 LogP 4.76390 InChIKey OBYNJKLOYWCXEP-UHFFFAOYSA-N SMILES CN(C)c1ccc2c(-c3cc(N=C=S)ccc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1 Storage condition 2~8°C |
| Use of | Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2]. Properties Name 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-4-isothiocyanatobenzoate Synonym More Synonyms Tetramethylrhodamine-6-isothiocyanate Biological Activity Description Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203. Chemical & Physical Properties Molecular Formula C25H21N3O3S Exact Mass 443.13000 PSA 104.20000 LogP 4.76390 InChIKey OBYNJKLOYWCXEP-UHFFFAOYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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