| Chemical & Physical Properties | |
|---|---|
| CAS Number | 80724-19-2 |
| Catalog No. | 2A-9048522 |
| Chinese Name | 四甲基罗丹明-5-异硫氰酸 |
| Synonyms | Xanthylium; Tetramethylrhodamine-5-isothiocyanate; 5-TRITC; 5-TRITC,G isomer; MFCD00467978 |
| Molecular Formula | C25H21N3O3S |
| Molecular Weight | 443.53 |
| Purity | 98.00 |
| Storage Condition | -20°C |
| Application | Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used to label PG-M3 antibodies for rapid diagnosis of acute promyelocytic leukemia (APL) |
| PubChem ID | 3190840 |
| MDL Number | C25H21N3O3S |
| SMILES | CN(C)c1ccc2c(-c3ccc(N=C=S)cc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1 |
| InChI | InChI=1S/C25H21N3O3S/c1-27(2)16-6-9-19-22(12-16)31-23-13-17(28(3)4)7-10-20(23)24(19)18-8-5-15(26-14-32)11-21(18)25(29)30/h5-13H,1-4H3 |
| InChI Key | IJSMFQNTEUNRPY-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/48522_1_80724_19_2.pdf |
| Bioactivity | Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Alayed KM, et al. Immunostaining for rapid diagnosis of acute promyelocytic leukemia with the tetramethylrhodamine-5-isothiocyanate-conjugated anti-promyelocytic leukemia monoclonal antibody PG-M3. Arch Pathol Lab Med. 2013 Nov;137(11):1669-73. [2]. Navarro SM, et al. Biodistribution of PLGA and PLGA/chitosan nanoparticles after repeat-dose oral delivery in F344 rats for 7 days. Ther Deliv. 2014 Nov;5(11):1191-201. Chemical & Physical Properties Molecular Formula C25H21N3O3S Molecular Weight 443.51800 Exact Mass 443.13000 PSA 104.20000 LogP 4.76390 InChIKey IJSMFQNTEUNRPY-UHFFFAOYSA-N SMILES CN(C)c1ccc2c(-c3ccc(N=C=S)cc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1 Storage condition -20°C |
| Use of | Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles[1][2]. Properties Name 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-isothiocyanatobenzoate Synonym More Synonyms Tetramethylrhodamine-5-isothiocyanate Biological Activity Description Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Alayed KM, et al. Immunostaining for rapid diagnosis of acute promyelocytic leukemia with the tetramethylrhodamine-5-isothiocyanate-conjugated anti-promyelocytic leukemia monoclonal antibody PG-M3. Arch Pathol Lab Med. 2013 Nov;137(11):1669-73. [2]. Navarro SM, et al. Biodistribution of PLGA and PLGA/chitosan nanoparticles after repeat-dose oral delivery in F344 rats for 7 days. Ther Deliv. 2014 Nov;5(11):1191-201. Chemical & Physical Properties Molecular Formula C25H21N3O3S Exact Mass 443.13000 PSA 104.20000 LogP 4.76390 InChIKey IJSMFQNTEUNRPY-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 90.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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