CAS Number79642-50-5
SynonymsN,N'-disuccinimidyl glutarate; 1,1'-[(1,5-Dioxo-1,5-pentanediyl)bis(oxy)]di(2,5-pyrrolidinedione); DISUCCINIMIDYL GLUTARATE; N-hydroxysuccinimide ester disuccinimidyl glutarate
Molecular FormulaC13H14N2O8
Molecular Weight326.26
Purity≥97.0 (CHN)%
Density1.5±0.1 g/cm3
Boiling Point485.1±55.0 °C at 760 mmHg
Appearancelumps
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 79642-50-5 |
| Catalog No. | 2A-9048368 |
| Chinese Name | 双琥珀酰亚胺戊二酸酯 |
| Synonyms | N,N'-disuccinimidyl glutarate; 1,1'-[(1,5-Dioxo-1,5-pentanediyl)bis(oxy)]di(2,5-pyrrolidinedione); DISUCCINIMIDYL GLUTARATE; N-hydroxysuccinimide ester disuccinimidyl glutarate |
| Molecular Formula | C13H14N2O8 |
| Molecular Weight | 326.26 |
| Purity | ≥97.0 (CHN) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 485.1±55.0 °C at 760 mmHg |
| Appearance | lumps |
| Storage Condition | -20°C |
| Application | DSG Crosslinker is a cleavable ADC linker used for the synthesis of antibody drug conjugates (ADC). |
| PubChem ID | 57652832 |
| MDL Number | MFCD00153597 |
| SMILES | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O |
| InChI | 1S/C13H14N2O8/c16-8-4-5-9(17)14(8)22-12(20)2-1-3-13(21)23-15-10(18)6-7-11(15)19/h1-7H2 |
| InChI Key | LNQHREYHFRFJAU-UHFFFAOYSA-N |
| Beilstein/REAXYS | 8575145 |
| NACRES Code | NA.25 |
| UNSPSC | 12161502 |
| Hazard Symbols | transportation |
| MSDS | msds/48368_1_79642_50_5.pdf |
| Bioactivity | DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology Target Cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Geng X, et al. Synthesis of the Oligosaccharides of Burkholderia pseudomallei and B. mallei Capsular Polysaccharide and Preliminary Immunological Studies of Their Protein Conjugates. J Org Chem. 2020 Feb 21;85(4):2369-2384. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 485.1±55.0 °C at 760 mmHg Molecular Formula C13H14N2O8 Molecular Weight 326.259 Flash Point 247.2±31.5 °C Exact Mass 326.075012 PSA 127.36000 LogP -3.30 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.572 InChIKey LNQHREYHFRFJAU-UHFFFAOYSA-N SMILES O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O Storage condition -20°C |
| Use of | DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Properties Articles73 Name bis(2,5-dioxopyrrolidin-1-yl) pentanedioate Synonym More Synonyms DSG Crosslinker Biological Activity Description DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Geng X, et al. Synthesis of the Oligosaccharides of Burkholderia pseudomallei and B. mallei Capsular Polysaccharide and Preliminary Immunological Studies of Their Protein Conjugates. J Org Chem. 2020 Feb 21;85(4):2369-2384. Chemical & Physical Properties Molecular Formula C13H14N2O8 Exact Mass 326.075012 PSA 127.36000 LogP -3.30 Index of Refraction 1.572 InChIKey LNQHREYHFRFJAU-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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