
CAS Number78247-49-1
SynonymsPOTASSIUMGUAIACOLSULFONATE,USP; Potassium hydroxymethoxybenzenesulfonate hemihydrate; hydroxymethoxy-benzenesulfonicacimonopotassiumsalt; PotassiuM guaiacolsulfonate heMihydrate API; PATSSIUMGUAIACOLSULFONATE; POTASSIUM GUAIACOLSULFONATE HYDRATE; Potassium 4-hydroxy-3-methoxybenzenesulfonate hydrate (2:2:1); Benzenesulfonic acid, 4-hydroxy-3-methoxy-, potassium salt, hydrate (2:2:1); PotassiuM Guaiacolsulfonate,HeMihydrate,USP
Molecular FormulaC7H8O5S.1/2H2O.K
Molecular Weight251.30
Purity98.00%
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 78247-49-1 |
| Catalog No. | 2A-9048201 |
| Chinese Name | 愈创木酚磺酸钾 |
| Synonyms | POTASSIUMGUAIACOLSULFONATE,USP; Potassium hydroxymethoxybenzenesulfonate hemihydrate; hydroxymethoxy-benzenesulfonicacimonopotassiumsalt; PotassiuM guaiacolsulfonate heMihydrate API; PATSSIUMGUAIACOLSULFONATE; POTASSIUM GUAIACOLSULFONATE HYDRATE; Potassium 4-hydroxy-3-methoxybenzenesulfonate hydrate (2:2:1); Benzenesulfonic acid, 4-hydroxy-3-methoxy-, potassium salt, hydrate (2:2:1); PotassiuM Guaiacolsulfonate,HeMihydrate,USP |
| Molecular Formula | C7H8O5S.1/2H2O.K |
| Molecular Weight | 251.30 |
| Purity | 98.00 |
| Storage Condition | -20°C |
| Application | Potassium guaiacolsulfonate hemihydrate 是一种具有口服活性祛痰剂,可用于急性呼吸道感染。Potassium guaiacolsulfonate hemihydrate 有助于松弛粘液,与其他药物合用,可用于由普通感冒,感染或过敏引起的咳嗽。 |
| HTC | 2909500000 |
| MDL Number | MFCD00064211 |
| SMILES | [K+].[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO |
| InChI | 1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1 |
| InChI Key | HLCFGWHYROZGBI-JJKGCWMISA-M |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/48201_1_78247_49_1.pdf |
| Bioactivity | Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other drugs[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial In Vitro Potassium guaiacolsulfonate hemihydrate works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up[1]. References [1]. Thi Huong Hoa Le, et al. Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. J Anal Methods Chem. 2019 Mar 7;2019:6143061. [2]. Ozlem Aksu Dönmez, et al. Simultaneous Determination of Potassium Guaiacolsulfonate, Guaifenesin, Diphenhydramine HCl and Carbetapentane Citrate in Syrups by Using HPLC-DAD Coupled With Partial Least Squares Multivariate Calibration. Talanta. 2011 Feb 15;83(5):1601-5. Chemical & Physical Properties Molecular Formula C7H8O5S.1/2H2O.K Molecular Weight 502.597 Exact Mass 501.940826 PSA 199.31000 LogP 2.70710 Storage condition -20°C |
| Use of | Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other drugs[1][2]. Properties Name Potassium guaiacolsulfonate hemihydrate Synonym More Synonyms Potassium guaiacolsulfonate hemihydrate Biological Activity Description Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other drugs[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial In Vitro Potassium guaiacolsulfonate hemihydrate works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up[1]. References [1]. Thi Huong Hoa Le, et al. Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. J Anal Methods Chem. 2019 Mar 7;2019:6143061. [2]. Ozlem Aksu Dönmez, et al. Simultaneous Determination of Potassium Guaiacolsulfonate, Guaifenesin, Diphenhydramine HCl and Carbetapentane Citrate in Syrups by Using HPLC-DAD Coupled With Partial Least Squares Multivariate Calibration. Talanta. 2011 Feb 15;83(5):1601-5. Chemical & Physical Properties Exact Mass 501.940826 PSA 199.31000 LogP 2.70710 |
| Tax Rebate | 9.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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