CAS Number76823-03-5
SynonymsMFCD00151081; 3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid; EINECS 276-331-1; 3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid; 5-carboxyfluorescein; 5-FAM
Molecular FormulaC21H12O7
Molecular Weight376.32
Purity98.00%
Density1.7±0.1 g/cm3
Boiling Point725.2±60.0 °C at 760 mmHg
Melting Point368-372°C
Appearanceorange solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 76823-03-5 |
| Catalog No. | 2A-0202223 |
| Chinese Name | 5-羧基荧光素 |
| Synonyms | MFCD00151081; 3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid; EINECS 276-331-1; 3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid; 5-carboxyfluorescein; 5-FAM |
| Molecular Formula | C21H12O7 |
| Molecular Weight | 376.32 |
| Purity | 98.00 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 725.2±60.0 °C at 760 mmHg |
| Melting Point | 368-372°C |
| Appearance | orange solid |
| Water Solubility | DMF: soluble |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | 5-FAM is an isomer of carboxyfluorescein. |
| HTC | 2932999099 |
| PubChem ID | 3190713 |
| SMILES | O=C(O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21 |
| InChI | InChI=1S/C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21/h1-9,22-23H,(H,24,25) |
| InChI Key | NJYVEMPWNAYQQN-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | The single isomer, 5-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 725.2±60.0 °C at 760 mmHg Melting Point 368-372°C Molecular Formula C21H12O7 Molecular Weight 376.316 Flash Point 266.9±26.4 °C Exact Mass 376.058289 PSA 113.29000 LogP 2.62 Vapour Pressure 0.0±2.5 mmHg at 25°C Index of Refraction 1.816 InChIKey NJYVEMPWNAYQQN-UHFFFAOYSA-N SMILES O=C(O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21 Storage condition Store at 2-8 Water Solubility DMF: soluble |
| Use of | The single isomer, 5-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser. Properties Articles65 Name 5-carboxyfluorescein Synonym More Synonyms 5-carboxyfluorescein Biological Activity Description The single isomer, 5-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others Chemical & Physical Properties Molecular Formula C21H12O7 Exact Mass 376.058289 PSA 113.29000 Index of Refraction 1.816 InChIKey NJYVEMPWNAYQQN-UHFFFAOYSA-N Storage condition Store at 2-8 Water Solubility DMF: soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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