CAS Number76822-21-4
SynonymsDanshensu; Sodium (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate; (2R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, sodium salt, (αR)- (1:1); Salvianic
Molecular FormulaC9H10O5
Molecular Weight198.18
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point481.5±40.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 76822-21-4 |
| Catalog No. | 2A-9048041 |
| Chinese Name | 丹参素 |
| Synonyms | Danshensu; Sodium (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate; (2R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, sodium salt, (αR)- (1:1); Salvianic |
| Molecular Formula | C9H10O5 |
| Molecular Weight | 198.18 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 481.5±40.0 °C at 760 mmHg |
| Storage Condition | Room temperature, dry, sealed |
| Application | Danshensu is the active ingredient of Salvia miltiorrhiza, which can activate the Nrf2 signaling pathway and protect cardiovascular disease. |
| HTC | 2942000000 |
| PubChem ID | 56378687 |
| MDL Number | MFCD09750417 |
| SMILES | O=C(O)C(O)Cc1ccc(O)c(O)c1 |
| InChI | InChI=1S/C9H10O5/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14/h1-3,8,10-12H,4H2,(H,13,14)/t8-/m1/s1 |
| InChI Key | PAFLSMZLRSPALU-MRVPVSSYSA-N |
| MSDS | msds/48041_1_76822_21_4.pdf |
| Use of | Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway. Properties Name (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid Synonym More Synonyms Danshensu Biological Activity Description Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway. Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Cardiovascular Disease Natural Products >> Phenylpropanoids In Vivo Acute treatment with a single dose of danshensu in rats with normal tHcy does not change plasma tHcy. In contrast, danshensu significantly lowers tHcy in rats with elevated tHcy. The relatively higher cysteine and glutathione levels after treatment with danshensu indicates that its tHcy-lowering effect is via increased activity of the trans-sulphuration pathway[1]. References [1]. YG Cao, et al. Beneficial effects of danshensu, an active component of Salvia miltiorrhiza, on homocysteine metabolism via the trans-sulphuration pathway in rats. Br J Pharmacol. 2009 Jun; 157(3): 482-490. Chemical & Physical Properties Molecular Formula C9H10O5 PSA 97.99000 LogP -0.29 Index of Refraction 1.659 InChIKey PAFLSMZLRSPALU-MRVPVSSYSA-N Safety Information Hazard Codes Xi HS Code 2942000000 |
| Transport Info | Product name: Danshensu |
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