| Chemical & Physical Properties | |
|---|---|
| CAS Number | 75498-96-3 |
| Catalog No. | 2A-9047879 |
| Chinese Name | 头孢米诺钠 |
| Synonyms | CefMinox SodiuM Salt Heptahydrate; Meicelin Heptahydrate; CefMinox SodiuM Heptahydrate; Cefminox sodium; Cefminox Sodium Salt |
| Molecular Formula | C16H20N7NaO7S3 |
| Molecular Weight | 541.557 |
| Purity | 98.00 |
| Appearance | powder |
| Storage Condition | Warehouse low temperature ventilation and drying |
| Application | Cefminox sodium (MT-141) is a semi-synthetic cephamycin with broad-spectrum antibacterial activity. Cefminox sodium (MT-141) is a dual agonist of prostacyclin receptor and PPARγ, which can upregulate |
| HTC | 3003201900 |
| PubChem ID | 12012783 |
| SMILES | COC1(NC(=O)CSCC(N)C(=O)[O-])C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC21.[H+].[Na+] |
| InChI | InChI=1S/C16H21N7O7S3.Na/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26;/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28);/q;+1/p-1/t8?,14-,16+;/m1./s1 |
| InChI Key | SBIDXLKJYJVQOE-YNJMIPHHSA-M |
| Use of | Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity[1]. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension[2]. Properties Name (6R-(6-α,7-α))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Synonym More Synonyms Cefminox sodium Biological Activity Description Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity[1]. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension[2]. Related Catalog Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Signaling Pathways >> Anti-infection >> Bacterial IP Receptor References [1]. Inouye S, et al. In vitro and in vivo antibacterial activities of MT-141, a new semisynthetic cephamycin, compared with those of five cephalosporins. Antimicrob Agents Chemother. 1984 Nov;26(5):722-9. [2]. Xia J, et al. Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats. Front Pharmacol. 2018 Feb 23;9:134. Chemical & Physical Properties Molecular Formula C16H20N7NaO7S3 Exact Mass 541.048401 PSA 281.59000 InChIKey SBIDXLKJYJVQOE-YNJMIPHHSA-M Safety Information HS Code 3003201900 |
| Transport Info | Product name: Cefminox sodium heptahydrate |
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