CAS Number62265-68-3
Synonyms1-(dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl 2-furoate; Quinfamido [INN-Spanish]; Quinfamide; Quinfamidum [INN-Latin]; 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline; EINECS 263-478-1; Amenide
Molecular FormulaC16H13O4N1Cl2
Molecular Weight354.19
Purity98.00%
Density1.428g/cm3
Boiling Point551.3ºC at 760mmHg
Melting Point145-146ºC
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 62265-68-3 |
| Catalog No. | 2A-9045687 |
| Chinese Name | 1-(二氯乙酰基)-6-(2-呋喃甲酰氧基)-1,2,3,4-四氢喹啉 |
| Synonyms | 1-(dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl 2-furoate; Quinfamido [INN-Spanish]; Quinfamide; Quinfamidum [INN-Latin]; 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline; EINECS 263-478-1; Amenide |
| Molecular Formula | C16H13O4N1Cl2 |
| Molecular Weight | 354.19 |
| Purity | 98.00 |
| Density | 1.428g/cm3 |
| Boiling Point | 551.3ºC at 760mmHg |
| Melting Point | 145-146ºC |
| Storage Condition | 2-8°C |
| Application | Quinfamide is an antiamoebic agent. Quinfamide can be used to treat amebiasis, helminthiasis and other tropical parasitic infections. |
| HTC | 2934999090 |
| PubChem ID | 7847707 |
| MDL Number | MFCD00864662 |
| SMILES | O=C(Oc1ccc2c(c1)CCCN2C(=O)C(Cl)Cl)c1ccco1 |
| InChI | InChI=1S/C16H13Cl2NO4/c17-14(18)15(20)19-7-1-3-10-9-11(5-6-12(10)19)23-16(21)13-4-2-8-22-13/h2,4-6,8-9,14H,1,3,7H2 |
| InChI Key | SBJGFIXQRZOVTO-UHFFFAOYSA-N |
| MSDS | msds/45687_1_62265_68_3.pdf |
| Use of | Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1]. Properties Name [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate Synonym More Synonyms Quinfamide Biological Activity Description Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1]. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. Davila-Gutierrez CE, et al. Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children. Am J Trop Med Hyg. 2002 Mar;66(3):251-4. Chemical & Physical Properties Exact Mass 353.02200 PSA 59.75000 LogP 3.64670 Index of Refraction 1.599 InChIKey SBJGFIXQRZOVTO-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester CAS REGISTRY NUMBER : 62265-68-3 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C16-H13-Cl2-N-O4 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979 Safety Information HS Code 2934999090 Synthetic Route Total: 1 Page 2-Furoyl chloride CAS#:527-69-5 1-(Dichloroacet... CAS#:62265-67-2 CAS#:7440-44-0 Quinfamide CAS#:62265-68-3 Literature: US3997542 A1, ; |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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