| Chemical & Physical Properties | |
|---|---|
| CAS Number | 53350-26-8 |
| Catalog No. | 2A-9043971 |
| Chinese Name | 5,7,3',4',5'-五甲氧基黄酮 |
| Synonyms | 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one |
| Molecular Formula | C20H20O7 |
| Molecular Weight | 372.37 |
| Purity | 98.00 |
| Density | 1.244g/cm3 |
| Boiling Point | 554.4ºC at 760mmHg |
| Melting Point | 198-200ºC |
| Appearance | Off-white crystalline solid |
| Storage Condition | 2-8°C |
| Application | 3',4',5',5,7-Pentamethoxyflavone is a natural brass compound extracted from Rutaceae. It overcomes the resistance of cancer cells to chemotherapy drugs by inhibiting the Nrf2 pathway. |
| HTC | 2914509090 |
| PubChem ID | 219172 |
| MDL Number | C20H20O7 |
| SMILES | COc1cc(OC)c2c(=O)cc(-c3cc(OC)c(OC)c(OC)c3)oc2c1 |
| InChI | InChI=1S/C20H20O7/c1-22-12-8-15(23-2)19-13(21)10-14(27-16(19)9-12)11-6-17(24-3)20(26-5)18(7-11)25-4/h6-10H,1-5H3 |
| InChI Key | GIKVSFNAEBQLGB-UHFFFAOYSA-N |
| MSDS | msds/43971_1_53350_26_8.pdf |
| Use of | 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1]. Properties Name 3',4',5',5,7-Pentamethoxyflavone Synonym More Synonyms 5,7,3',4',5'-Pentamethoxyflavone Biological Activity Description 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References Chemical & Physical Properties Molecular Formula C20H20O7 Exact Mass 372.12100 PSA 76.36000 LogP 3.50300 Index of Refraction 1.565 InChIKey GIKVSFNAEBQLGB-UHFFFAOYSA-N Safety Information HS Code 2914509090 Synthetic Route (Z)-2-(2-bromo-... 392302-51-1 5,7,3',4... 53350-26-8 Literature: Bose, Gopal; Mondal, Ejabul; Khan, Abu T; Bordoloi, Manob J. Tetrahedron Letters, 2001 , vol. 42, # 50 p. 8907 - 8909 1-(4,6-dimethox... 84212-57-7 5,7,3',4... 53350-26-8 Literature: Briggs, Malcolm T.; Duncan, Graham L. S.; Thornber, Craig W. Journal of Chemical Research, Miniprint, 1982 , # 9 p. 2461 - 2487 Xanthoxylin Trimethylgalloy... 5,7,3',4... 53350-26-8 Literature: Mateeva, Nelly N.; Kode, Rao N.; Redda, Kinfe K. Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 6 p. 1251 - 1258 Precursor & DownStream Precursor 10 CAS#:392302-51-1 (Z)-2-(2-bromo-... CAS#:84212-57-7 1-(4,6-dimethox... CAS#:90-24-4 Xanthoxylin CAS#:4521-61-3 Trimethylgalloy... DownStream 1 CAS#:118-41-2 Trimethylgallic acid |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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| Nile Blue A perchlorate | 53340-16-2 | 2A-9043967 |
| 9,10-Diaminophenanthrene | 53348-04-2 | 2A-9043969 |
| 3,6-Dibromo-9,10-phenanthrenequinone | 53348-05-3 | 2A-9043970 |
| Diethyl 2-(4-(benzyloxy)benzylidene)malonate | 53361-40-3 | 2A-9043972 |
| Sodium O,O-diisobutyl dithiophosphate | 53378-51-1 | 2A-9043976 |
| cis-3-Hexenyl 2-methylbutanoate | 53398-85-9 | 2A-9043977 |
| Ethyl 2-methyl-4-pentenoate | 53399-81-8 | 2A-9043978 |
| 5,6,7,8-Tetrahydro-5-quinolinone | 53400-41-2 | 2A-9043979 |
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