CAS Number50402-56-7
Synonyms5-(2-Aminoethylamino)-1-naphthalenesulfonic acid; 1,5-EDANS (N-(Aminoethyl)-5-naphthylamine-1-sulfonic acid; 5-(2-aminoethylamino)naphthalene-1-sulfonic acid; MFCD00066932; EINECS 256-575-5
Molecular FormulaC12H14O3N2S1
Molecular Weight266.32
Purity98.00%
Density1.432 g/cm3
Melting Point>350°C
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 50402-56-7 |
| Catalog No. | 2A-9043243 |
| Chinese Name | 5-(2-氨基乙氨基)-1-萘磺酸 |
| Synonyms | 5-(2-Aminoethylamino)-1-naphthalenesulfonic acid; 1,5-EDANS (N-(Aminoethyl)-5-naphthylamine-1-sulfonic acid; 5-(2-aminoethylamino)naphthalene-1-sulfonic acid; MFCD00066932; EINECS 256-575-5 |
| Molecular Formula | C12H14O3N2S1 |
| Molecular Weight | 266.32 |
| Purity | 98.00 |
| Density | 1.432 g/cm3 |
| Melting Point | >350°C |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | EDANS (1,5-EDANS) is a novel quenched fluorogenic substrate for the analysis of retroviral proteases via resonance energy transfer. |
| HTC | 2921590090 |
| PubChem ID | 3157745 |
| MDL Number | MFCD00066932 |
| SMILES | NCCNc1cccc2c(S(=O)(=O)O)cccc12 |
| InChI | InChI=1S/C12H14N2O3S/c13-7-8-14-11-5-1-4-10-9(11)3-2-6-12(10)18(15,16)17/h1-6,14H,7-8,13H2,(H,15,16,17) |
| InChI Key | SJQRQOKXQKVJGJ-UHFFFAOYSA-N |
| MSDS | msds/43243_1_50402_56_7.pdf |
| Bioactivity | EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1]. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1]. References [1]. E D Matayoshi, et al. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 1990 Feb 23;247(4945):954-8. Chemical & Physical Properties Density 1.432 g/cm3 Melting Point >350°C Molecular Formula C12H14N2O3S Molecular Weight 266.31600 Exact Mass 266.07300 PSA 100.80000 LogP 3.31120 Index of Refraction 1.691 InChIKey SJQRQOKXQKVJGJ-UHFFFAOYSA-N SMILES NCCNc1cccc2c(S(=O)(=O)O)cccc12 Storage condition Refrigerator |
| Use of | EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1]. Properties Name N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Synonym More Synonyms EDANS Biological Activity Description EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1]. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1]. References [1]. E D Matayoshi, et al. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 1990 Feb 23;247(4945):954-8. Chemical & Physical Properties Molecular Formula C12H14N2O3S Exact Mass 266.07300 PSA 100.80000 LogP 3.31120 Index of Refraction 1.691 InChIKey SJQRQOKXQKVJGJ-UHFFFAOYSA-N Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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