
CAS Number43139-22-6
Synonymsguanosine 5'-diphosphate sodium salt,Type I; GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT; guanosine 5'-diphosphate sodium type I; 5'-GDP 3NA; GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE; Guanosine-5''-diphosphoric acid monosodium salt
Molecular FormulaC10H14N5NaO11P2
Molecular Weight443.20
Purity≥96 (HPLC)%
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 43139-22-6 |
| Catalog No. | 2A-9043082 |
| Chinese Name | 5'-二磷酸鸟苷钠盐 |
| Synonyms | guanosine 5'-diphosphate sodium salt,Type I; GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT; guanosine 5'-diphosphate sodium type I; 5'-GDP 3NA; GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE; Guanosine-5''-diphosphoric acid monosodium salt |
| Molecular Formula | C10H14N5NaO11P2 |
| Molecular Weight | 443.20 |
| Purity | ≥96 (HPLC) |
| Appearance | powder |
| Storage Condition | 20°C |
| Application | Sodium guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channels. Sodium guanosine-5'-biphosphate is a potential iron mobilizer that pre |
| PubChem ID | 24895291 |
| MDL Number | MFCD00070121 |
| SMILES | [Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O)c2N1 |
| InChI | 1S/C10H15N5O11P2.Na.H/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);; |
| InChI Key | PVMPTWQLNDHIEV-UHFFFAOYSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| MSDS | msds/43082_1_43139_22_6.pdf |
| Bioactivity | Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Target Human Endogenous Metabolite References [1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. [2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097. Chemical & Physical Properties Molecular Formula C10H14N5NaO11P2 Molecular Weight 465.18200 Exact Mass 465.00600 PSA 275.02000 InChIKey RIVKOZCPUDVJCY-GWTDSMLYSA-N SMILES Nc1nc2c(ncn2C2OC(COP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1.[Na] Storage condition 20°C |
| Use of | Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2]. Properties Name guanosine 5'-diphosphate sodium salt Synonym More Synonyms guanosine 5'-diphosphate sodium salt Biological Activity Description Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Human Endogenous Metabolite References [1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. Chemical & Physical Properties Molecular Formula C10H14N5NaO11P2 Exact Mass 465.00600 PSA 275.02000 InChIKey RIVKOZCPUDVJCY-GWTDSMLYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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