CAS Number39665-12-8
SynonymsL-Lysine monohydrate; L-Lysine hydrate; lysine,hydrate; L-LYS H2O; LYS,MONOHYDRATE; EINECS 200-294-2; H-Lys-OH H2O; MFCD00151035
Molecular FormulaNH2(CH2)4CH(NH2)COOH
Molecular Weight146.19 (anhydrous basis)
Purity98.00%
Boiling Point400ºC at 760 mmHg
Melting Point207-209 °C (decomposes)
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 39665-12-8 |
| Catalog No. | 2A-9042383 |
| Chinese Name | L-赖氨酸一水物 |
| Synonyms | L-Lysine monohydrate; L-Lysine hydrate; lysine,hydrate; L-LYS H2O; LYS,MONOHYDRATE; EINECS 200-294-2; H-Lys-OH H2O; MFCD00151035 |
| Molecular Formula | NH2(CH2)4CH(NH2)COOH |
| Molecular Weight | 146.19 (anhydrous basis) |
| Purity | 98.00 |
| Boiling Point | 400ºC at 760 mmHg |
| Melting Point | 207-209 °C (decomposes) |
| Appearance | solid |
| Water Solubility | >1500 g/L (20 ºC) |
| Storage Condition | Sealed, cool and dry storage |
| Application | Hydrated lysine is an essential amino acid. Hydrated lysine can be used to study vascular calcification (VC) and acute pancreatitis [1][2]. |
| HTC | 2922411000 |
| PubChem ID | 24857062 |
| MDL Number | MFCD00151035 |
| SMILES | [N+H3][C@@H](CCCCN)C(=O)[O-].O |
| InChI | 1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1 |
| InChI Key | HZRUTVAFDWTKGD-JEDNCBNOSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352209 |
| Hazard Symbols | transportation |
| MSDS | msds/42383_1_39665_12_8.pdf |
| Bioactivity | L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2]. Related Catalog Research Areas >> Others Research Areas >> Inflammation/Immunology Target Microbial Metabolite Human Endogenous Metabolite In Vitro L-Lysine hydrate (VSMCs) suppresses plasma iPTH and elevates plasma alanine, proline, plasma arginine, and homo arginine, thereby inhibiting apoptosis of VSMCs and mineral precipitation[1]. In Vivo L-Lysine hydrate (40 μg/kg; p.o.) ameliorates arterial calcification in adenine rats and protects the femora from osteoporotic changes in adenine rats[1]. L-Lysine hydrate (10 and 400 mg/kg; i.g. and p.o.; Male mice) inhibits pancreatic tissue damage[2]. Animal Model: Male mice[2] Dosage: 10 and 400 mg/kg Administration: Intraperitoneal injection and oral administration; for 15 days Result: Inhibited the release of the inflammatory cytokine IL-6 and enhance antioxidant activity. References [1]. Shimomura A, et, al. Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [2]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193. Chemical & Physical Properties Boiling Point 400ºC at 760 mmHg Melting Point 212-214 °C Molecular Formula C6H16N2O3 Molecular Weight 164.20300 Flash Point 195.7ºC Exact Mass 164.11600 PSA 98.57000 LogP 0.86360 InChIKey HZRUTVAFDWTKGD-JEDNCBNOSA-N SMILES NCCCCC(N)C(=O)O.O Water Solubility >1500 g/L (20 ºC) |
| Use of | L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2]. Properties Articles13 Name L(+)-Lysine monohydrate Synonym More Synonyms L(+)-Lysine monohydrate Biological Activity Description L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2]. Related Catalog Research Areas >> Others Research Areas >> Inflammation/Immunology Microbial Metabolite Human Endogenous Metabolite In Vitro L-Lysine hydrate (VSMCs) suppresses plasma iPTH and elevates plasma alanine, proline, plasma arginine, and homo arginine, thereby inhibiting apoptosis of VSMCs and mineral precipitation[1]. References [1]. Shimomura A, et, al. Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [2]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193. Chemical & Physical Properties Molecular Formula C6H16N2O3 Exact Mass 164.11600 PSA 98.57000 LogP 0.86360 InChIKey HZRUTVAFDWTKGD-JEDNCBNOSA-N SMILES NCCCCC(N)C(=O)O.O |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | P. Quarantine of entry animals, plants, and animal and plant products Q. Quarantine of exit animals, plants, and animal and plant products R. Hygiene supervision and inspection of imported food S. Hyg |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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