CAS Number38862-24-7
SynonymsN-SucciniMidyl Acrylate; 1-(Acryloyloxy)pyrrolidine-2,5-dione; N-acryloxysuccinimide; N-Acryloyloxysuccinimide; Acrylic Acid N-Succinimidyl Ester; 1-(Acryloyloxy)-2,5-pyrrolidinedione; 2,5-Dioxopyrrolidin-1-yl acrylate; MFCD00078261; 1-[(1-Oxo-2-propenyl)oxy]-2,5-pyrrolidinedione
Molecular FormulaC7H7NO4
Molecular Weight169.13
Purity≥90 (HPLC)%
Density1.3±0.1 g/cm3
Boiling Point251.3±23.0 °C at 760 mmHg
Melting Point69 °C
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 38862-24-7 |
| Catalog No. | 2A-9042216 |
| Chinese Name | N-羟基琥珀酰亚胺丙烯酸酯 |
| Synonyms | N-SucciniMidyl Acrylate; 1-(Acryloyloxy)pyrrolidine-2,5-dione; N-acryloxysuccinimide; N-Acryloyloxysuccinimide; Acrylic Acid N-Succinimidyl Ester; 1-(Acryloyloxy)-2,5-pyrrolidinedione; 2,5-Dioxopyrrolidin-1-yl acrylate; MFCD00078261; 1-[(1-Oxo-2-propenyl)oxy]-2,5-pyrrolidinedione |
| Molecular Formula | C7H7NO4 |
| Molecular Weight | 169.13 |
| Purity | ≥90 (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 251.3±23.0 °C at 760 mmHg |
| Melting Point | 69 °C |
| Appearance | solid |
| Water Solubility | Soluble in: Toluene |
| Storage Condition | Sealed in a cool, dry environment at 2-8℃ |
| Application | 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein cross-linker. 2,5-Dioxopyrrolidin-1-yl acrylate reacts with monoclonal anti-horseradish peroxidase IgG antibodies to modify lys |
| HTC | 2925190090 |
| PubChem ID | 57653888 |
| MDL Number | MFCD00078261 |
| SMILES | C=CC(=O)ON1C(=O)CCC1=O |
| InChI | 1S/C7H7NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2H,1,3-4H2 |
| InChI Key | YXMISKNUHHOXFT-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352005 |
| MSDS | msds/42216_1_38862_24_7.pdf |
| Bioactivity | 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1]. Related Catalog Research Areas >> Others References [1]. Okyem S, et, al. High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates. Bioconjug Chem. 2021 Aug 18;32(8):1753-1762. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 251.3±23.0 °C at 760 mmHg Melting Point 69 °C Molecular Formula C7H7NO4 Molecular Weight 169.135 Flash Point 105.8±22.6 °C Exact Mass 169.037506 PSA 63.68000 LogP -1.21 Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.520 InChIKey YXMISKNUHHOXFT-UHFFFAOYSA-N SMILES C=CC(=O)ON1C(=O)CCC1=O Storage condition 2-8°C |
| Use of | 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1]. Properties Name N-Acryloxysuccinimide Synonym More Synonyms N-acryloxysuccinimide Biological Activity Description 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1]. Related Catalog Research Areas >> Others References [1]. Okyem S, et, al. High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates. Bioconjug Chem. 2021 Aug 18;32(8):1753-1762. Chemical & Physical Properties Molecular Formula C7H7NO4 Exact Mass 169.037506 PSA 63.68000 LogP -1.21 Index of Refraction 1.520 InChIKey YXMISKNUHHOXFT-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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