CAS Number28957-04-2
SynonymsORIDONIN; Rubescensin; ISODONAL; (1α,5β,6β,7β,8α,9β,10α,13α,14R)-1,6,7,14-Tetrahydroxy-7,20-epoxykaur-16-en-15-one; RUBESCENSIN A; 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one Isodonol; Isodonol; megathyrin A; Rabdosia rubescens
Molecular FormulaC20H28O6
Molecular Weight364.433
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point599.8±50.0 °C at 760 mmHg
Melting Point248-250ºC
AppearanceSolid;White to Almost white powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 28957-04-2 |
| Catalog No. | 2A-9040490 |
| Chinese Name | 冬凌草甲素 |
| Synonyms | ORIDONIN; Rubescensin; ISODONAL; (1α,5β,6β,7β,8α,9β,10α,13α,14R)-1,6,7,14-Tetrahydroxy-7,20-epoxykaur-16-en-15-one; RUBESCENSIN A; 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one Isodonol; Isodonol; megathyrin A; Rabdosia rubescens |
| Molecular Formula | C20H28O6 |
| Molecular Weight | 364.433 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 599.8±50.0 °C at 760 mmHg |
| Melting Point | 248-250ºC |
| Appearance | Solid;White to Almost white powder to crystal |
| Water Solubility | DMSO: >20mg/mL |
| Storage Condition | 2-8°C |
| Application | Oridonin is a diterpene obtained from Rabdosia rubescens. It is an AKT inhibitor with IC50 values of 8.4 and 8.9 μM for AKT1 and AKT2 respectively. Oridonin has anti-tumor, antibacterial, anti-infla |
| HTC | 2942000000 |
| SMILES | C=C1C(=O)C23C(O)C1CCC2C12COC3(O)C(O)C1C(C)(C)CCC2O |
| InChI Key | SDHTXBWLVGWJFT-RDQYUEOQSA-N |
| Use of | Oridonin, a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects. Properties Articles29 Biological Activity Chemical & Physical Properties Toxicological Info Safety Info Precursor & Downstream |
| Transport Info | Product Name: Rubescens A |
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