CAS Number28166-41-8
Synonyms(2E)-2-Cyano-3-(4-hydroxyphenyl)acrylic acid; Ganaxolone; 4-HCCA; α-cyano-4-hydroxycinnamic acid; 2-Cyano-3-(4-hydroxyphenyl)acrylic Acid; alpha-Cyano-4-hydroxycinnamic acid; MFCD00004204; (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid; EINECS 248-879-1; A-CYANO-4-HYDROXYCINNAMIC ACID; ACCA
Molecular FormulaC10H7NO3
Molecular Weight189.167
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point398.1±32.0 °C at 760 mmHg
Melting Point245-250 °C(lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 28166-41-8 |
| Catalog No. | 2A-9040346 |
| Chinese Name | α-氰基-4-羟基肉桂酸 |
| Synonyms | (2E)-2-Cyano-3-(4-hydroxyphenyl)acrylic acid; Ganaxolone; 4-HCCA; α-cyano-4-hydroxycinnamic acid; 2-Cyano-3-(4-hydroxyphenyl)acrylic Acid; alpha-Cyano-4-hydroxycinnamic acid; MFCD00004204; (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid; EINECS 248-879-1; A-CYANO-4-HYDROXYCINNAMIC ACID; ACCA |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.167 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 398.1±32.0 °C at 760 mmHg |
| Melting Point | 245-250 °C(lit.) |
| Appearance | powder |
| Water Solubility | methanol: 10 mg/mL, clear |
| Storage Condition | Sealed, store at 2 ºC -8 ºC |
| Application | α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent, non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits the mitochondrial pyr |
| HTC | 2926909090 |
| SMILES | N#CC(=Cc1ccc(O)cc1)C(=O)O |
| InChI | InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+ |
| InChI Key | AFVLVVWMAFSXCK-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/40346_2_28166_41_8.pdf |
| Bioactivity | Chemical & Physical Properties |
| Use of | α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications[1][2]. Properties Articles103 Biological Activity Chemical & Physical Properties |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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