CAS Number26171-23-3
Synonyms[3H]-Tolmetin; [1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid; EINECS 247-497-2; Tolmetino; Tolmetine; Tolmetina; TOLMETIN; Tolmetinum; 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid; Tolectin; 5-(p-toluoyl)-1-methylpyrrole-2-acetic acid; 5-(4-methylbenzoyl)-1-methyl-pyrrol-2-ylacetic acid; 1-Methyl-5-p-toluoylpyrrole-2-acetic acid; Tolmetine [INN-French]; 2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid; 1-methyl-5-(4-methylbenzoyl)pyrrol-2-acetic acid; 1-Methyl-5-(p-toluoyl)-2-pyrroleacetic acid; Tolmetina [DCIT]; 1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid; 1-METHYL-5-P-TOLUOYL-PYRROLE-2-ACETIC ACID
Molecular FormulaC15H15NO3
Molecular Weight257.284
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point483.2±40.0 °C at 760 mmHg
Melting Point156ºC
AppearanceOff-white crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 26171-23-3 |
| Catalog No. | 2A-9039888 |
| Chinese Name | 托麦汀 |
| Synonyms | [3H]-Tolmetin; [1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid; EINECS 247-497-2; Tolmetino; Tolmetine; Tolmetina; TOLMETIN; Tolmetinum; 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid; Tolectin; 5-(p-toluoyl)-1-methylpyrrole-2-acetic acid; 5-(4-methylbenzoyl)-1-methyl-pyrrol-2-ylacetic acid; 1-Methyl-5-p-toluoylpyrrole-2-acetic acid; Tolmetine [INN-French]; 2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid; 1-methyl-5-(4-methylbenzoyl)pyrrol-2-acetic acid; 1-Methyl-5-(p-toluoyl)-2-pyrroleacetic acid; Tolmetina [DCIT]; 1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid; 1-METHYL-5-P-TOLUOYL-PYRROLE-2-ACETIC ACID |
| Molecular Formula | C15H15NO3 |
| Molecular Weight | 257.284 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 483.2±40.0 °C at 760 mmHg |
| Melting Point | 156ºC |
| Appearance | Off-white crystalline powder |
| Water Solubility | 222 mg/L |
| Storage Condition | Store under inert gas; avoid air |
| Application | Tolmetin is an orally active and potent COX inhibitor with IC50 values of 0.35 µM and 0.82 µM for human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal substance with potent anti-inflamma |
| HTC | 2933990090 |
| SMILES | Cc1ccc(C(=O)c2ccc(CC(=O)O)n2C)cc1 |
| InChI | InChI=1S/C15H15NO3.Na/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18;/h3-8H,9H2,1-2H3,(H,17,18);/q;+1/p-1 |
| InChI Key | UPSPUYADGBWSHF-UHFFFAOYSA-N |
| Use of | Tolmetin is an orally active and potent COX inhibitor with IC50s of 0.35 µM and 0.82 µM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID)[1][2]. Properties Biological Activity Chemical & Physical Properties Toxicological Info Safety Info Synthetic Route Precursor & Downstream |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 3,4-Dimethylbenzamidine | 26130-47-2 | 2A-9039876 |
| Morantel tartrate | 26155-31-7 | 2A-9039880 |
| Polyquaternium-37 | 26161-33-1 | 2A-9039883 |
| 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one | 26167-45-3 | 2A-9039886 |
| 3-Acetylthianaphthene | 26168-40-1 | 2A-9039887 |
| Isothiazolinones; 5-Chloro-2-methyl-4-isothiazolin-3-one | 26172-55-4 | 2A-9039890 |
| 3-Nitrobenzylammonium hydrochloride | 26177-43-5 | 2A-9039891 |
| D-Fructose-6-phosphate disodium salt | 26177-86-6 | 2A-9039893 |
| 1-Chloro-N,N,2-trimethylpropenylamine | 26189-59-3 | 2A-9039896 |
| 4'-Methyl[1,1'-biphenyl]-4-ol | 26191-64-0 | 2A-9039897 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS