CAS Number23601-40-3
Synonyms2,5,8,11,14,17-Hexaoxanonadecan-19-ol; hexa-PEG monomethyl ether; methoxy polyethyleneglycol tosylate; methoxyhexaethylene glycol; EINECS 245-775-8; 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol; 3,6,9,12,15,18-Hexaoxanonadecan-1-ol; Hexaethylene glycol monomethyl ether
Molecular FormulaC13H28O7
Molecular Weight296.36
Purity98.00%
Density1.1±0.1 g/cm3
Boiling Point375.6±37.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 23601-40-3 |
| Catalog No. | 2A-9039289 |
| Chinese Name | 六乙二醇一甲醚 |
| Synonyms | 2,5,8,11,14,17-Hexaoxanonadecan-19-ol; hexa-PEG monomethyl ether; methoxy polyethyleneglycol tosylate; methoxyhexaethylene glycol; EINECS 245-775-8; 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol; 3,6,9,12,15,18-Hexaoxanonadecan-1-ol; Hexaethylene glycol monomethyl ether |
| Molecular Formula | C13H28O7 |
| Molecular Weight | 296.36 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 375.6±37.0 °C at 760 mmHg |
| Storage Condition | Room temperature, dry, sealed |
| Application | Hexaethylene glycol monomethyl ether is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| HTC | 2909499000 |
| MDL Number | MFCD00045996 |
| SMILES | COCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C13H28O7/c1-15-4-5-17-8-9-19-12-13-20-11-10-18-7-6-16-3-2-14/h14H,2-13H2,1H3 |
| InChI Key | FHHGCKHKTAJLOM-UHFFFAOYSA-N |
| MSDS | msds/39289_1_23601_40_3.pdf |
| Bioactivity | Hexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 375.6±37.0 °C at 760 mmHg Molecular Formula C13H28O7 Molecular Weight 296.357 Flash Point 180.9±26.5 °C Exact Mass 296.183502 PSA 75.61000 LogP -2.59 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.446 InChIKey FHHGCKHKTAJLOM-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOCCOCCO |
| Use of | Hexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name hexaethylene glycol monomethyl ether Synonym More Synonyms 2,5,8,11,14,17-Hexaoxanonadecan-19-ol Biological Activity Description Hexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C13H28O7 Exact Mass 296.183502 PSA 75.61000 LogP -2.59 Index of Refraction 1.446 InChIKey FHHGCKHKTAJLOM-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOCCOCCO |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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