CAS Number19771-63-2
SynonymsL-2-Oxothiazolidine-4-carboxylic Acid; 2-oxothiazolidine-4(R)-carboxylic acid; 4-Thiazolidinecarboxylic acid,2-oxo-,(R)-[]; OTCA; L-2-Oxothiazolidine-4-carboxylate; (4R)-2-Oxothiazolidine-4-carboxylic acid; (R)-(−)-2-Oxothiazolidine-4-carboxylic acid L-(−)-2-Oxothiazolidine-4-carboxylic acid; L-2-Oxo-4-thiazolidinecarboxylic acid; (R)-2-oxothiazolidine-4-carboxylic acid; L-(−)-2-Oxothiazolidine-4-carboxylic acid; (4R)-2-Oxo-1,3-thiazolidine-4-carboxylic acid; (−)-2-Oxo-4-thiazolidinecarboxylic acid; MFCD00066092; Procysteine; Oxothiazolidine carboxylate,L; (4R)-2-oxo-4-thiazolidine-carboxylic acid; (4R)-2-Hydroxy-4,5-dihydro-1,3-thiazole-4-carboxylic acid; L-2-Thiazolidinone-4-carboxylic Acid; 2-Oxothiazolidine-4-carboxylate,L; (R)-(−)-2-Oxothiazolidine-4-carboxylic acid
Molecular FormulaC4H5NO3S
Molecular Weight147.15
Purity≥97 (TLC)%
Density1.6±0.1 g/cm3
Melting Point174 °C (dec.)(lit.)
Appearance(powder to crystals)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 19771-63-2 |
| Catalog No. | 2A-9038207 |
| Chinese Name | L-2-噻唑林二酮-4-甲酸 |
| Synonyms | L-2-Oxothiazolidine-4-carboxylic Acid; 2-oxothiazolidine-4(R)-carboxylic acid; 4-Thiazolidinecarboxylic acid,2-oxo-,(R)-[]; OTCA; L-2-Oxothiazolidine-4-carboxylate; (4R)-2-Oxothiazolidine-4-carboxylic acid; (R)-(−)-2-Oxothiazolidine-4-carboxylic acid L-(−)-2-Oxothiazolidine-4-carboxylic acid; L-2-Oxo-4-thiazolidinecarboxylic acid; (R)-2-oxothiazolidine-4-carboxylic acid; L-(−)-2-Oxothiazolidine-4-carboxylic acid; (4R)-2-Oxo-1,3-thiazolidine-4-carboxylic acid; (−)-2-Oxo-4-thiazolidinecarboxylic acid; MFCD00066092; Procysteine; Oxothiazolidine carboxylate,L; (4R)-2-oxo-4-thiazolidine-carboxylic acid; (4R)-2-Hydroxy-4,5-dihydro-1,3-thiazole-4-carboxylic acid; L-2-Thiazolidinone-4-carboxylic Acid; 2-Oxothiazolidine-4-carboxylate,L; (R)-(−)-2-Oxothiazolidine-4-carboxylic acid |
| Molecular Formula | C4H5NO3S |
| Molecular Weight | 147.15 |
| Purity | ≥97 (TLC) |
| Density | 1.6±0.1 g/cm3 |
| Melting Point | 174 °C (dec.)(lit.) |
| Appearance | (powder to crystals) |
| Storage Condition | 2-8℃ |
| Application | Oxothiazolidinecarboxylic acid is an antioxidant and a prodrug of cysteine. It is inert and metabolized into cysteine within cells, thereby stimulating the synthesis of glutathione. |
| HTC | 2934999090 |
| PubChem ID | 24898032 |
| MDL Number | MFCD00066092 |
| SMILES | OC(=O)[C@@H]1CSC(=O)N1 |
| InChI | 1S/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1 |
| InChI Key | BMLMGCPTLHPWPY-REOHCLBHSA-N |
| Beilstein/REAXYS | 4179169 |
| NACRES Code | NA.26 |
| UNSPSC | 12352106 |
| MSDS | msds/38207_1_19771_63_2.pdf |
| Bioactivity | Oxothiazolidinecarboxylic acid, an antioxidant, is a prodrug of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vivo Oxothiazolidinecarboxylic acid treatment attenuates plantaris atrophy, restored glutathione levels, and increased catalase, Cu/Zn-SOD1, and Mn-SOD2 mRNA expression, but did not reduce other markers of oxidant stress or levels of these catabolic factors[1]. Animal Model: Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group)[1]. Dosage: 0.35% (w/v). Administration: Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk. Result: Increased fiber CSAs compared to the non-supplemented, alcohol-fed group. References [1]. Jeffrey S Otis, et al. Procysteine Stimulates Expression of Key Anabolic Factors and Reduces Plantaris Atrophy in Alcohol-Fed Rats. Alcohol Clin Exp Res. 2009 Aug;33(8):1450-9. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Melting Point 174 °C (dec.)(lit.) Molecular Formula C4H5NO3S Molecular Weight 147.152 Exact Mass 146.999008 PSA 91.70000 LogP -1.11 Index of Refraction 1.595 InChIKey BMLMGCPTLHPWPY-REOHCLBHSA-N SMILES O=C1NC(C(=O)O)CS1 |
| Use of | Oxothiazolidinecarboxylic acid, an antioxidant, is a prodrug of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis[1]. Properties Articles28 Name (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid Synonym More Synonyms Oxothiazolidinecarboxylic acid Biological Activity Description Oxothiazolidinecarboxylic acid, an antioxidant, is a prodrug of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Jeffrey S Otis, et al. Procysteine Stimulates Expression of Key Anabolic Factors and Reduces Plantaris Atrophy in Alcohol-Fed Rats. Alcohol Clin Exp Res. 2009 Aug;33(8):1450-9. Chemical & Physical Properties Molecular Formula C4H5NO3S Exact Mass 146.999008 PSA 91.70000 LogP -1.11 Index of Refraction 1.595 InChIKey BMLMGCPTLHPWPY-REOHCLBHSA-N SMILES O=C1NC(C(=O)O)CS1 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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