CAS Number2316-26-9
SynonymsRARECHEM BK HC T253; 3-(3,4-Dimethoxyphenyl)-2-propenoic Acid; 3,4-Dimethoxy cinnamic acid; 3,4-Dimethoxycinnamic acid; EINECS 219-025-5; 3-(3,4-Dimethoxyphenyl)acrylic acid; o-Methylferulic acid; 3,4-Dimethoxy; 3,4-Dimethoxycinnami; DIMETHYLCAFFEIC ACID; 3,4-Dimethoxycinnamic Acid, Predominantly trans; 3-(3,4-dimethoxyphenyl)propenoic acid; 3,4-Dimethoxycinnamic Acid,Predominantly trans; MFCD00004387; Methylferulic acid
Molecular Formula(CH3O)2C6H3CH=CHCO2H
Molecular Weight208.21
Purity99%
Density1.2±0.1 g/cm3
Boiling Point367.4±27.0 °C at 760 mmHg
Melting Point181-183 °C (lit.)
Appearancepowder
EINECS219-025-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2316-26-9 |
| Catalog No. | 2A-9003801 |
| Chinese Name | 3,4-二甲氧基肉桂酸 |
| Synonyms | RARECHEM BK HC T253; 3-(3,4-Dimethoxyphenyl)-2-propenoic Acid; 3,4-Dimethoxy cinnamic acid; 3,4-Dimethoxycinnamic acid; EINECS 219-025-5; 3-(3,4-Dimethoxyphenyl)acrylic acid; o-Methylferulic acid; 3,4-Dimethoxy; 3,4-Dimethoxycinnami; DIMETHYLCAFFEIC ACID; 3,4-Dimethoxycinnamic Acid, Predominantly trans; 3-(3,4-dimethoxyphenyl)propenoic acid; 3,4-Dimethoxycinnamic Acid,Predominantly trans; MFCD00004387; Methylferulic acid |
| Molecular Formula | (CH3O)2C6H3CH=CHCO2H |
| Molecular Weight | 208.21 |
| Purity | 99 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 367.4±27.0 °C at 760 mmHg |
| Melting Point | 181-183 °C (lit.) |
| Appearance | powder |
| Storage Condition | -20°C |
| Application | 3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells through th |
| EINECS | 219-025-5 |
| HTC | 2916399090 |
| PubChem ID | 24893261 |
| MDL Number | MFCD00004387 |
| SMILES | COc1ccc(\C=C\C(O)=O)cc1OC |
| InChI | 1S/C11H12O4/c1-14-9-5-3-8(4-6-11(12)13)7-10(9)15-2/h3-7H,1-2H3,(H,12,13)/b6-4+ |
| InChI Key | HJBWJAPEBGSQPR-GQCTYLIASA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| Risk Codes | R36/37/38 |
| Safety Description | S26;S37/39 |
| MSDS | msds/3801_1_2316_26_9.pdf |
| Bioactivity | 3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1]. Related Catalog Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Research Areas >> Cancer Research Areas >> Infection Natural Products >> Phenylpropanoids In Vitro 3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells[1]. 3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner[1]. References [1]. Li L, et al. Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signalingpathway. Int J Oncol. 2018 Jul;53(1):225-236. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 367.4±27.0 °C at 760 mmHg Melting Point 181-183 °C(lit.) Molecular Formula C11H12O4 Molecular Weight 208.211 Flash Point 144.0±17.2 °C Exact Mass 208.073563 PSA 55.76000 LogP 2.24 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.574 Storage condition -20°C |
| Use of | Properties Name 3,4-Dimethoxycinnamic acid Synonym More Synonyms 3,4-Dimethoxycinnamic acid Biological Activity Related Catalog Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Research Areas >> Cancer Research Areas >> Infection Natural Products >> Phenylpropanoids References Chemical & Physical Properties Molecular Formula C11H12O4 Exact Mass 208.073563 PSA 55.76000 Index of Refraction 1.574 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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| 3,4-Dimethylbenzyl alcohol | 6966-10-5 | 2A-9003809 |
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