CAS Number7460-43-7
Synonyms9,10-Anthracenedione,3-hydroxy-1-methoxy-2-methyl; 3-Hydroxy-1-methoxy-2-methylanthraquinone; 1,3-dimethoxy-2-methylanthraquinone; 3-Hydroxy-1-methoxy-2-methyl-anthraquinone; 3-Hydroxy-1-methoxy-2-methyl-9,10-anthraquinone; rubiadin-1-methyl ether; 3-Hydroxy-1-methoxy-2-methyl-anthrachinon
Molecular FormulaC16H12O4
Molecular Weight268.27
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point502.2±50.0 °C at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 7460-43-7 |
| Catalog No. | 2A-9033709 |
| Chinese Name | 甲基异茜草素-1-甲醚 |
| Synonyms | 9,10-Anthracenedione,3-hydroxy-1-methoxy-2-methyl; 3-Hydroxy-1-methoxy-2-methylanthraquinone; 1,3-dimethoxy-2-methylanthraquinone; 3-Hydroxy-1-methoxy-2-methyl-anthraquinone; 3-Hydroxy-1-methoxy-2-methyl-9,10-anthraquinone; rubiadin-1-methyl ether; 3-Hydroxy-1-methoxy-2-methyl-anthrachinon |
| Molecular Formula | C16H12O4 |
| Molecular Weight | 268.27 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 502.2±50.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8℃, dry, sealed |
| Application | Rubiadin-1-methyl ether is an anthraquinone compound in Morinda officinalis, which can inhibit osteoclastic bone resorption by inhibiting the phosphorylation level of NF-κB p65, degrading IκBα protein |
| HTC | 2914690090 |
| MDL Number | C16H12O4 |
| SMILES | COc1c(C)c(O)cc2c1C(=O)c1ccccc1C2=O |
| InChI | InChI=1S/C16H12O4/c1-8-12(17)7-11-13(16(8)20-2)15(19)10-6-4-3-5-9(10)14(11)18/h3-7,17H,1-2H3 |
| InChI Key | NTBUBTCXACOEEC-UHFFFAOYSA-N |
| MSDS | msds/33709_1_7460_43_7.pdf |
| Use of | Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1]. Properties Name rubiadin 1-methyl ether Synonym More Synonyms Rubiadin 1-methyl ether Biological Activity Description Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1]. References [1]. He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931. Chemical & Physical Properties Molecular Formula C16H12O4 Exact Mass 268.073547 PSA 63.60000 Index of Refraction 1.649 InChIKey NTBUBTCXACOEEC-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2914690090 Synthetic Route Total: 1 Page CAS#:117-02-2 Dimethyl sulfate CAS#:77-78-1 Rubiadin 1-meth... CAS#:7460-43-7 Literature: Molecules, , vol. 18, # 8 p. 10042 - 10055 3-acetoxy-1-met... CAS#:2324-25-6 Rubiadin 1-meth... CAS#:7460-43-7 Literature: Journal of the Chemical Society, , p. 1699,1707 CAS#:117-02-2 Rubiadin 1-meth... CAS#:7460-43-7 Literature: Journal of the Chemical Society [Section] C: Organic, , p. 854 - 857 Precursor & DownStream Precursor 3 CAS#:117-02-2 CAS#:77-78-1 Dimethyl sulfate CAS#:2324-25-6 3-acetoxy-1-met... DownStream 2 CAS#:117-02-2 CAS#:3736-59-2 NORDAMNACANTAL |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Methylisorubicin-1-methyl ether |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Aluminium chloride | 7446-70-0 | 2A-9033698 |
| Sodium acrylate | 7446-81-3 | 2A-9033699 |
| Cupric chloride | 7447-39-4 | 2A-9033700 |
| Mordant Violet 1 | 7452-51-9 | 2A-9033704 |
| Ethyl 2-methylbutyrate | 7452-79-1 | 2A-9033705 |
| 2,3-Dimethoxycinnamic acid | 7461-60-1 | 2A-9033712 |
| 3'-Acetamidoacetophenone | 7463-31-2 | 2A-9033714 |
| 2-(4-Nitrophenyl)butyric acid | 7463-53-8 | 2A-9033716 |
| 1,7-Dimethyl-3-isobutylxanthine | 7464-84-8 | 2A-9033719 |
| 4-Morpholinobenzoic acid | 7470-38-4 | 2A-9033722 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS