CAS Number6645-46-1
Synonyms(−)-β-Hydroxy-γ-(trimethylammonio)butyrate; 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; 3-Hydroxy-4-(trimethylammonio)butanoate hydrochloride; Vitamin BT Hydrochloride; Carnitine chloride; L-CARNITINE HYDROCHLORIDE; 3-Hydroxy-4-(trimethylammonio)butyrate Hydrochloride; (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; MFCD00066100; L(-)-Carnitine hydrochloride; [(2R)-3-carboxy-2-hydroxypropyl]-trimethylazanium,chloride; (2R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt, hydrochloride (1:1); LEVOCARNITINE HYDROCHLORIDE; (R)-3-Hydroxy-4-(trimethylammonio)butanoate hydrochloride; 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt, hydrochloride (1:1); (2R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; QV1YQ1K1&1
Molecular Formula(CH3)3N+CH2CH(OH)CH2CO2H · Cl-
Molecular Weight197.66
Purity≥98%
Melting Point142 °C
Appearancepowder
EINECS229-663-6
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6645-46-1 |
| Catalog No. | 2A-9033067 |
| Chinese Name | 左旋肉碱盐酸盐 |
| Synonyms | (−)-β-Hydroxy-γ-(trimethylammonio)butyrate; 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; 3-Hydroxy-4-(trimethylammonio)butanoate hydrochloride; Vitamin BT Hydrochloride; Carnitine chloride; L-CARNITINE HYDROCHLORIDE; 3-Hydroxy-4-(trimethylammonio)butyrate Hydrochloride; (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; MFCD00066100; L(-)-Carnitine hydrochloride; [(2R)-3-carboxy-2-hydroxypropyl]-trimethylazanium,chloride; (2R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt, hydrochloride (1:1); LEVOCARNITINE HYDROCHLORIDE; (R)-3-Hydroxy-4-(trimethylammonio)butanoate hydrochloride; 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt, hydrochloride (1:1); (2R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; QV1YQ1K1&1 |
| Molecular Formula | (CH3)3N+CH2CH(OH)CH2CO2H · Cl- |
| Molecular Weight | 197.66 |
| Purity | ≥98 |
| Melting Point | 142 °C |
| Appearance | powder |
| Water Solubility | soluble |
| Storage Condition | Warehouse low temperature ventilation and drying |
| Application | L-Carnitine hydrochloride is a highly polar small zwitterion and an important co-factor in the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride works by transporting long-chain fatty acyl- |
| EINECS | 229-663-6 |
| HTC | 2923900090 |
| PubChem ID | 24892246 |
| MDL Number | MFCD00066100 |
| SMILES | [Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O |
| InChI | 1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1 |
| InChI Key | JXXCENBLGFBQJM-FYZOBXCZSA-N |
| NACRES Code | NA.79 |
| UNSPSC | 12352106 |
| Hazard Symbols | transportation |
| MSDS | msds/33067_1_6645_46_1.pdf |
| Bioactivity | L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3]. Related Catalog Research Areas >> Metabolic Disease Target Human Endogenous Metabolite In Vivo L-Carnitine hydrochloride ((R)-Carnitine hydrochloride) (125, 250 mg/kg; i.p.) has a more pronounced bronchodilator effect in this chronic murine asthma model, and decreases urinary LTE4 excretion[4]. Animal Model: 8- to 10-weeks-old and weighed 28-30g BALB/c mice[4] Dosage: 125, 250 mg/kg Administration: i.p. Result: SaO2 increased significantly at 250 mg/kg and decreased urinaryLTE4 excretion. References [1]. Agarwal A, et al. Role of L-carnitine in female infertility. eprod Biol Endocrinol. 2018 Jan 26;16(1):5. [2]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [3]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [4]. Uzuner N, et al. The role of L-carnitine in treatment of a murine model of asthma. Acta Med Okayama. 2002 Dec;56(6):295-301. Chemical & Physical Properties Melting Point 142 °C Molecular Formula C7H16ClNO3 Molecular Weight 197.660 Exact Mass 197.081863 PSA 60.36000 InChIKey JXXCENBLGFBQJM-FYZOBXCZSA-N SMILES C[N+](C)(C)CC(O)CC(=O)O.[Cl-] Water Solubility soluble |
| Use of | L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3]. Properties Name L-Carnitine hydrochloride Synonym More Synonyms L-Carnitine hydrochloride Biological Activity Description L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3]. Related Catalog Research Areas >> Metabolic Disease Human Endogenous Metabolite References [1]. Agarwal A, et al. Role of L-carnitine in female infertility. eprod Biol Endocrinol. 2018 Jan 26;16(1):5. [2]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [3]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [4]. Uzuner N, et al. The role of L-carnitine in treatment of a murine model of asthma. Acta Med Okayama. 2002 Dec;56(6):295-301. Chemical & Physical Properties Exact Mass 197.081863 PSA 60.36000 InChIKey JXXCENBLGFBQJM-FYZOBXCZSA-N SMILES C[N+](C)(C)CC(O)CC(=O)O.[Cl-] Water Solubility soluble |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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