
CAS Number614-60-8
Synonyms(2E)-3-(2-Hydroxyphenyl)-2-propenoic acid; (2E)-3-(2-Hydroxyphenyl)acrylic acid; (E)-o-coumaric acid; trans-2-coumaric acid; o-Coumaric acid; (E)-3-(2-Hydroxyphenyl)-2-propenoic acid; Coumaric acid; o-Hydroxy-trans-cinnamic acid; QV1U1R BQ &&E or trans Form; (E)-3-(2-Hydroxyphenyl)acrylic acid; (2E)-3-(2-Hydroxyphenyl)prop-2-enoic acid; EINECS 210-386-4; trans-2-Hydroxycinnamic acid; trans-o-Coumaric Acid; trans-o-Hydroxycinnamic acid; o-Hydroxycinnamic acid; 2-Hydroxycinnamic acid; (E)-2-Hydroxycinnamic acid; (E)-o-Hydroxycinnamic acid; (E)-3-(2-Hydroxyphenyl)prop-2-enoic acid; MFCD00004379; ortho-Hydroxycinnamic acid
Molecular FormulaHOC6H4CH=CHCO2H
Molecular Weight164.16
Purity97%
Density1.3±0.1 g/cm3
Boiling Point348.0±17.0 °C at 760 mmHg
Melting Point217 °C (dec.) (lit.)
AppearanceOff-white to beige powder
EINECS210-386-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 614-60-8 |
| Catalog No. | 2A-9003272 |
| Chinese Name | 2-羟基肉桂酸; 邻羟基肉桂酸 |
| Synonyms | (2E)-3-(2-Hydroxyphenyl)-2-propenoic acid; (2E)-3-(2-Hydroxyphenyl)acrylic acid; (E)-o-coumaric acid; trans-2-coumaric acid; o-Coumaric acid; (E)-3-(2-Hydroxyphenyl)-2-propenoic acid; Coumaric acid; o-Hydroxy-trans-cinnamic acid; QV1U1R BQ &&E or trans Form; (E)-3-(2-Hydroxyphenyl)acrylic acid; (2E)-3-(2-Hydroxyphenyl)prop-2-enoic acid; EINECS 210-386-4; trans-2-Hydroxycinnamic acid; trans-o-Coumaric Acid; trans-o-Hydroxycinnamic acid; o-Hydroxycinnamic acid; 2-Hydroxycinnamic acid; (E)-2-Hydroxycinnamic acid; (E)-o-Hydroxycinnamic acid; (E)-3-(2-Hydroxyphenyl)prop-2-enoic acid; MFCD00004379; ortho-Hydroxycinnamic acid |
| Molecular Formula | HOC6H4CH=CHCO2H |
| Molecular Weight | 164.16 |
| Purity | 97 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 348.0±17.0 °C at 760 mmHg |
| Melting Point | 217 °C (dec.) (lit.) |
| Appearance | Off-white to beige powder |
| Storage Condition | Storage: Seal the container and store it in a seal |
| Application | 2-Hydroxycinnamic acid was isolated from the methanol extract of cinnamon. 2-Hydroxycinnamic acid has an inhibitory effect on HIV/SARS-CoV S pseudovirus infection with an IC50 of 0.3 mM[2] |
| EINECS | 210-386-4 |
| PubChem ID | 24895158 |
| MDL Number | MFCD00004379 |
| SMILES | OC(=O)\C=C\c1ccccc1O |
| InChI | 1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)/b6-5+ |
| InChI Key | PMOWTIHVNWZYFI-AATRIKPKSA-N |
| Beilstein/REAXYS | 1100900 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/3272_2_614_60_8.pdf |
| Bioactivity | 2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM[2] Related Catalog Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV Target HIV References [1]. Tran Minh Ngoc, et al. A new coumarin and cytotoxic activities of constituents from Cinnamomum cassia. Nat Prod Commun. 2014 Apr;9(4):487-8. [2]. Min Zhuang, et al. Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Antiviral Res. 2009 Apr;82(1):73-81. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 348.0±17.0 °C at 760 mmHg Melting Point 217ºC Molecular Formula C9H8O3 Molecular Weight 164.158 Flash Point 178.5±17.4 °C Exact Mass 164.047348 PSA 57.53000 LogP 2.43 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.660 InChIKey PMOWTIHVNWZYFI-AATRIKPKSA-N SMILES O=C(O)C=Cc1ccccc1O |
| Use of | Properties Articles13 Name 2-Hydroxy Cinnamic Acid Synonym More Synonyms 2-Hydroxycinnamic acid Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV References [1]. Tran Minh Ngoc, et al. A new coumarin and cytotoxic activities of constituents from Cinnamomum cassia. Nat Prod Commun. 2014 Apr;9(4):487-8. [2]. Min Zhuang, et al. Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Antiviral Res. 2009 Apr;82(1):73-81. Chemical & Physical Properties Molecular Formula C9H8O3 Exact Mass 164.047348 PSA 57.53000 Index of Refraction 1.660 InChIKey PMOWTIHVNWZYFI-AATRIKPKSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (trans-2-Hydroxycinnamic acid) IMDG Code: TOXIC SOLID, ORGANIC, N.O.S. (trans-2-Hydroxycinnamic acid) International air transport hazard regulations: Toxic solid, organic, n.o.s. (trans-2-Hydroxycinnamic acid) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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