CAS Number5725-91-7
Synonyms7-Ethoxy-3H-phenoxazin-3-one; MFCD00037661; 7-Ethoxyresorufin; 7-Ethoxy Resorufin; 7-ethoxyphenoxazin-3-one; Resorufin ethyl ether
Molecular FormulaC14H11NO3
Molecular Weight241.24
Purity≥95 (UV)%
Density1.3±0.1 g/cm3
Boiling Point389.3±42.0 °C at 760 mmHg
Melting Point223-225 °C (lit.)
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5725-91-7 |
| Catalog No. | 2A-9032101 |
| Chinese Name | 乙氧基试卤灵 |
| Synonyms | 7-Ethoxy-3H-phenoxazin-3-one; MFCD00037661; 7-Ethoxyresorufin; 7-Ethoxy Resorufin; 7-ethoxyphenoxazin-3-one; Resorufin ethyl ether |
| Molecular Formula | C14H11NO3 |
| Molecular Weight | 241.24 |
| Purity | ≥95 (UV) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 389.3±42.0 °C at 760 mmHg |
| Melting Point | 223-225 °C (lit.) |
| Appearance | solid |
| Storage Condition | 2-8℃, avoid light, keep in a cool and dry place, s |
| Application | 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorogenic substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase. |
| PubChem ID | 329757074 |
| MDL Number | MFCD00037661 |
| SMILES | CCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1.Fc4c(F)c(F)c(OC(=O)CNC(=O)OCC5c6ccccc6-c7ccccc57)c(F)c4F |
| InChI | 1S/C23H14F5NO4.C14H11NO3/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15;1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h1-8,15H,9-10H2,(H,29,31);3-8H,2H2,1H3 |
| InChI Key | ZOSYTBPPLWBBKM-UHFFFAOYSA-N |
| Beilstein/REAXYS | 225973 |
| NACRES Code | NA.32 |
| UNSPSC | 12161501 |
| MSDS | msds/32101_1_5725_91_7.pdf |
| Bioactivity | 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Others Signaling Pathways >> Immunology/Inflammation >> NO Synthase References [1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62. [2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 389.3±42.0 °C at 760 mmHg Melting Point 223-225ºC(lit.) Molecular Formula C14H11NO3 Molecular Weight 241.242 Flash Point 185.9±22.3 °C Exact Mass 241.073898 PSA 52.33000 LogP 2.02 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.624 InChIKey CRCWUBLTFGOMDD-UHFFFAOYSA-N SMILES CCOc1ccc2nc3ccc(=O)cc-3oc2c1 Storage condition -20°C |
| Use of | 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2]. Properties Articles56 Name 7-ethoxyresorufin Synonym More Synonyms 7-Ethoxyresorufin Biological Activity Description 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Others Signaling Pathways >> Immunology/Inflammation >> NO Synthase References [1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62. [2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90. Chemical & Physical Properties Molecular Formula C14H11NO3 Exact Mass 241.073898 PSA 52.33000 Index of Refraction 1.624 InChIKey CRCWUBLTFGOMDD-UHFFFAOYSA-N |
| Transport Info | Product Name: Ethoxyresorufin |
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