CAS Number951-78-0
SynonymsUracildeoxyr; deoxyuridine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-2(1H)-pyrimidinone; T6NVMVJ A- ET5OTJ B1Q CQ &&Ribo-β-D Form; 2'-deoxy-uridin; 1-(2-Deoxy-b-D-erythro-pentofuranosyl)uracil; [131I]-Deoxyuridine; 2'-Deoxyuridine; Desoxyuridine; MFCD00006527; 2'-dU; EINECS 213-455-7; 1-(2-Deoxy-D-erythro-pentofuranosyl)uracil; Deoxyribose uracil; 1-(2-deoxy-β-D-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione; Deoxy-uridin; 2′-Deoxyuridine; [3H]-Deoxyuridine; 1-(2-deoxy-β-D-erythro-pentofuranosyl)uracil; 1-(2-deoxy-β-δ-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; durd; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione; 1-(2-deoxy-β-δ-ribofuranosyl)-2,4
Molecular FormulaC9H12N2O5
Molecular Weight228.20
Purity≥98.5%
Density1.5±0.1 g/cm3
Melting Point167-169 °C(lit.)
Appearancepowder
EINECS213-455-7
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 951-78-0 |
| Catalog No. | 2A-9003063 |
| Chinese Name | 2'-脱氧尿苷 |
| Synonyms | Uracildeoxyr; deoxyuridine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-2(1H)-pyrimidinone; T6NVMVJ A- ET5OTJ B1Q CQ &&Ribo-β-D Form; 2'-deoxy-uridin; 1-(2-Deoxy-b-D-erythro-pentofuranosyl)uracil; [131I]-Deoxyuridine; 2'-Deoxyuridine; Desoxyuridine; MFCD00006527; 2'-dU; EINECS 213-455-7; 1-(2-Deoxy-D-erythro-pentofuranosyl)uracil; Deoxyribose uracil; 1-(2-deoxy-β-D-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione; Deoxy-uridin; 2′-Deoxyuridine; [3H]-Deoxyuridine; 1-(2-deoxy-β-D-erythro-pentofuranosyl)uracil; 1-(2-deoxy-β-δ-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; durd; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione; 1-(2-deoxy-β-δ-ribofuranosyl)-2,4 |
| Molecular Formula | C9H12N2O5 |
| Molecular Weight | 228.20 |
| Purity | ≥98.5 |
| Density | 1.5±0.1 g/cm3 |
| Melting Point | 167-169 °C(lit.) |
| Appearance | powder |
| Water Solubility | 300 g/L (20 ºC) |
| Storage Condition | Keep container sealed and stored in a cool, dry pl |
| Application | 2'-Deoxyuridine can promote chromosome breakage, thereby reducing the synthetic activity of thymidylate. It is also a precursor for the synthesis of Edoxudine. |
| EINECS | 213-455-7 |
| PubChem ID | 24893831 |
| MDL Number | MFCD00006527 |
| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N2C=CC(=O)NC2=O |
| InChI | 1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1 |
| InChI Key | MXHRCPNRJAMMIM-SHYZEUOFSA-N |
| Beilstein/REAXYS | 24433 |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| MSDS | msds/3063_1_951_78_0.pdf |
| Bioactivity | 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine. Related Catalog Research Areas >> Infection Natural Products >> Saccharides and Glycosides Target Human Endogenous Metabolite References [1]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Melting Point 167-169 °C(lit.) Molecular Formula C9H12N2O5 Molecular Weight 228.202 Exact Mass 228.074615 PSA 104.55000 LogP -1.70 Index of Refraction 1.603 InChIKey MXHRCPNRJAMMIM-UHFFFAOYSA-N SMILES O=c1ccn(C2CC(O)C(CO)O2)c(=O)[nH]1 Storage condition 0-6°C Water Solubility 300 g/L (20 ºC) |
| Use of | 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine. Properties Articles46 Name 2'-deoxyuridine Synonym More Synonyms 2'-deoxyuridine Biological Activity Description 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine. Related Catalog Research Areas >> Infection Natural Products >> Saccharides and Glycosides Human Endogenous Metabolite References [1]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5. Chemical & Physical Properties Molecular Formula C9H12N2O5 Exact Mass 228.074615 PSA 104.55000 LogP -1.70 Index of Refraction 1.603 InChIKey MXHRCPNRJAMMIM-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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