EN
0
Home > Products > Pharmaceuticals & Life Science > Biotechnology & Diagnostics > 2'-Deoxy-2'-fluorocytidine
2'-Deoxy-2'-fluorocytidine structure, CAS 10212-20-1

2'-Deoxy-2'-fluorocytidine

CAS Number10212-20-1

Synonyms2'-Deoxy-2'-fluorocytidine; 2'-FdC; MFCD00057445; 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one; 2'-Deoxy-2'-fluoro-D-cytidine; 2'-FLUORO-D-CYTIDINE; 2'-FC; 2`-Deoxy-2`-fluoro Cytidine; RO-8013; 2′-Fluoro-2′-deoxycytidine; 2'-Fluoro-2'-deoxycytidine

Molecular FormulaC9H12FN3O4

Molecular Weight245.208

Purity99%

Density1.8±0.1 g/cm3

Boiling Point500.1±60.0 °C at 760 mmHg

Melting Point167ºC

Flash Point

AppearanceWhite or almost white crystalline powder

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9003051 Purity: 99%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 10212-20-1 ] Purity: 99% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number10212-20-1
Catalog No.2A-9003051
Chinese Name2'-脱氧-2-氟胞苷
Synonyms2'-Deoxy-2'-fluorocytidine; 2'-FdC; MFCD00057445; 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one; 2'-Deoxy-2'-fluoro-D-cytidine; 2'-FLUORO-D-CYTIDINE; 2'-FC; 2`-Deoxy-2`-fluoro Cytidine; RO-8013; 2′-Fluoro-2′-deoxycytidine; 2'-Fluoro-2'-deoxycytidine
Molecular FormulaC9H12FN3O4
Molecular Weight245.208
Purity99
Density1.8±0.1 g/cm3
Boiling Point500.1±60.0 °C at 760 mmHg
Melting Point167ºC
AppearanceWhite or almost white crystalline powder
Water SolubilitySoluble in: methanol
Storage ConditionSeal in a cool, dry place.
Application2'-Deoxy-2'-fluorocytidine is a nucleoside analog that is a potent inhibitor of Congo hemorrhagic fever virus (CCHFV) replication. 2'-Deoxy-2'-fluorocytidine synergizes with T705 to enhance the antivi
HTC2934999090
SMILESNc1ccn(C2OC(CO)C(O)C2F)c(=O)n1
InChIInChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)
InChI KeyNVZFZMCNALTPBY-XVFCMESISA-N
Hazard SymbolsTransport
MSDSmsds/3051_1_10212_20_1.pdf
Bioactivity2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection In Vitro 2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC50) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC50) of >50.0 μM in Huh7 cells[1]. References [1]. Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 500.1±60.0 °C at 760 mmHg Melting Point 167ºC Molecular Formula C9H12FN3O4 Molecular Weight 245.208 Flash Point 256.2±32.9 °C Exact Mass 245.081177 PSA 110.60000 LogP -1.26 Vapour Pressure 0.0±2.9 mmHg at 25°C Index of Refraction 1.697 InChIKey NVZFZMCNALTPBY-XVFCMESISA-N SMILES Nc1ccn(C2OC(CO)C(O)C2F)c(=O)n1 Storage condition 2-8°C
Use of2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1]. Properties Name 2'-Deoxy-2'-fluorocytidine Synonym More Synonyms 2'-Deoxy-2'-fluorocytidine Biological Activity Description 2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection References [1]. Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99. Chemical & Physical Properties Molecular Formula C9H12FN3O4 Exact Mass 245.081177 PSA 110.60000 LogP -1.26 Index of Refraction 1.697 InChIKey NVZFZMCNALTPBY-XVFCMESISA-N
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
Related Products in Biotechnology & Diagnostics
2-Aminoadenosine2096-10-82A-9002439
2'-Chloro-2'-deoxycytidine10212-19-82A-9002790
2'-Chloro-2'-deoxyuridine4753-04-22A-9002791
2-Chloroadenosine146-77-02A-9002972
2-Chloroadenosine hemidydrate81012-94-42A-9002973
2'-Deoxy-2'-fluorouridine784-71-42A-9003052
2'-Deoxyadenosine958-09-82A-9003053
2'-Deoxyadenosine-5'-monophosphate902-04-52A-9003054
2'-Deoxycytidine951-77-92A-9003055
2'-Deoxycytidine hydrochloride3992-42-52A-9003056
Browse all Biotechnology & Diagnostics products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA