CAS Number3943-74-6
Synonyms4-Hydroxy-3-methoxybenzoic Acid Methyl Ester; Methyl 4-hydroxy-3-methoxybenzoate; MFCD00008438; Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester; Vanillic Acid Methyl Ester; Methyl vanillate; EINECS 223-525-9
Molecular FormulaHOC6H3(OCH3)CO2CH3
Molecular Weight182.17
Purity99%
Density1.2±0.1 g/cm3
Boiling Point285-287 °C (lit.)
Melting Point64-67 °C (lit.)
Appearancesolid
EINECS223-525-9
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3943-74-6 |
| Catalog No. | 2A-9030314 |
| Chinese Name | 香草酸甲酯 |
| Synonyms | 4-Hydroxy-3-methoxybenzoic Acid Methyl Ester; Methyl 4-hydroxy-3-methoxybenzoate; MFCD00008438; Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester; Vanillic Acid Methyl Ester; Methyl vanillate; EINECS 223-525-9 |
| Molecular Formula | HOC6H3(OCH3)CO2CH3 |
| Molecular Weight | 182.17 |
| Purity | 99 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 285-287 °C (lit.) |
| Melting Point | 64-67 °C (lit.) |
| Appearance | solid |
| Storage Condition | Store at room temperature, away from light, in a v |
| Application | Methyl vanillate is an extract from the Hovenia genus plant and is an activator of the Wnt/β-catenin signaling pathway [1]. Benzoate is the methyl ester of vanillic acid. It has antioxidant properties |
| EINECS | 223-525-9 |
| HTC | 2918990090 |
| PubChem ID | 24848233 |
| MDL Number | MFCD00008438 |
| SMILES | COC(=O)c1ccc(O)c(OC)c1 |
| InChI | 1S/C9H10O4/c1-12-8-5-6(9(11)13-2)3-4-7(8)10/h3-5,10H,1-2H3 |
| InChI Key | BVWTXUYLKBHMOX-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/30314_1_3943_74_6.pdf |
| Bioactivity | Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite. Related Catalog Signaling Pathways >> Stem Cell/Wnt >> Wnt Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology Target Wnt/β-catenin[1] In Vitro Methyl vanillate (0-100 μM) increases the expression and nuclear translocation of β-catenin in calvarial osteoblasts. Methyl vanillate dose-dependently elevates ALP activity in calvarial osteoblasts[1]. References [1]. Cha PH, et al. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. PLoS One. 2014 Jan 22;9(1):e85546. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 286.0±0.0 °C at 760 mmHg Melting Point 64-67 °C(lit.) Molecular Formula C9H10O4 Molecular Weight 182.173 Flash Point 120.2±15.8 °C Exact Mass 182.057907 PSA 55.76000 LogP 1.54 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.534 InChIKey BVWTXUYLKBHMOX-UHFFFAOYSA-N SMILES COC(=O)c1ccc(O)c(OC)c1 Storage condition Room temperature. |
| Use of | Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite. Properties Name methyl vanillate Synonym More Synonyms Methyl vanillate Biological Activity Description Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite. Related Catalog Signaling Pathways >> Stem Cell/Wnt >> Wnt Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology Wnt/β-catenin[1] In Vitro Methyl vanillate (0-100 μM) increases the expression and nuclear translocation of β-catenin in calvarial osteoblasts. Methyl vanillate dose-dependently elevates ALP activity in calvarial osteoblasts[1]. References [1]. Cha PH, et al. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. PLoS One. 2014 Jan 22;9(1):e85546. Chemical & Physical Properties Molecular Formula C9H10O4 Exact Mass 182.057907 PSA 55.76000 Index of Refraction 1.534 InChIKey BVWTXUYLKBHMOX-UHFFFAOYSA-N Storage condition Room temperature. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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