CAS Number3301-79-9
Synonyms6-carboxy-fluorescein; 6-Carboxyfluorescein; 3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid; 6-FAM; 6-FAM Hydrate; Carboxyfluorescein; MFCD00036873; 6-FAM,6-CF; 6-FAM FLUOS; EINECS 276-331-1; 6-FAM,FLUOS
Molecular FormulaC21H12O7
Molecular Weight376.32
Purity98.00%
Density1.7±0.1 g/cm3
Boiling Point736.4±60.0 °C at 760 mmHg
Melting Point>300 °C(lit.)
Appearanceorange solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3301-79-9 |
| Catalog No. | 2A-9029657 |
| Chinese Name | 6-羧基荧光素 |
| Synonyms | 6-carboxy-fluorescein; 6-Carboxyfluorescein; 3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid; 6-FAM; 6-FAM Hydrate; Carboxyfluorescein; MFCD00036873; 6-FAM,6-CF; 6-FAM FLUOS; EINECS 276-331-1; 6-FAM,FLUOS |
| Molecular Formula | C21H12O7 |
| Molecular Weight | 376.32 |
| Purity | 98.00 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 736.4±60.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Appearance | orange solid |
| Water Solubility | DMSO: soluble |
| Storage Condition | Store in airtight, cool and dry place |
| Application | 6-FAM is an isomer of carboxyfluorescein and is mainly used for nucleic acid sequencing and labeling. |
| HTC | 2915900090 |
| PubChem ID | 3190714 |
| SMILES | O=C(O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21 |
| InChI | InChI=1S/C21H12O7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h1-9,22-23H,(H,24,25) |
| InChI Key | BZTDTCNHAFUJOG-UHFFFAOYSA-N |
| Bioactivity | The single isomer, 6-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Dye Reagents Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 736.4±60.0 °C at 760 mmHg Melting Point >300 °C(lit.) Molecular Formula C21H12O7 Molecular Weight 376.316 Flash Point 271.0±26.4 °C Exact Mass 376.058289 PSA 113.29000 LogP 2.66 Vapour Pressure 0.0±2.5 mmHg at 25°C Index of Refraction 1.816 InChIKey BZTDTCNHAFUJOG-UHFFFAOYSA-N SMILES O=C(O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21 Storage condition 2-8°C Water Solubility DMSO: soluble |
| Use of | The single isomer, 6-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser. Properties Articles222 Name 6-carboxyfluorescein Synonym More Synonyms 6-Carboxyfluorescein Biological Activity Description The single isomer, 6-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Dye Reagents Chemical & Physical Properties Molecular Formula C21H12O7 Exact Mass 376.058289 PSA 113.29000 Index of Refraction 1.816 InChIKey BZTDTCNHAFUJOG-UHFFFAOYSA-N Water Solubility DMSO: soluble |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards 6-Carboxyfluorescein Hydrate Modification Number: 6 Module 14. Shipping information UN number: not specified |
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